The current US administration is edging towards a policy of developing new types of nuclear weapons. In today's uncertain world, the last thing we need is a renewed arms race among the world's nuclear powers.
doi:10.1038/428451a
Table of contents
Volume 428 Number 6982 pp451-586
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Top of page
Editorials
Playing a dangerous game p451
A fair deal for all p451
Scientists in poorer countries have to pay over the odds for equipment and reagents. They deserve a helping hand.
doi:10.1038/428451b
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News
High prices of supplies drain cash from poorer nations' labs p453
Bioterror tester kits trouble federal agencies p454
Rebelling scientists welcome left's landslide in France p454
Democrats slam Bush plan for fresh nuclear weapons p455
Australia considers revised scheme for young researchers p455
Founder bows out as genomic firm slashes workforce p456
Biologists get ball rolling to aid neglected invertebrates p456
Defence work sheds light on hospital bacteria p457
Letters to the Editor deliver fitting April message p457
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News Features
Information technology: In the know p462
In big groups and companies, it's hard to track who knows what. So how can scientists share information and prevent work being duplicated? Philip Ball investigates one solution: knowledge-management software.
Philip Ball
doi:10.1038/428462a
Laboratory animals: The Renaissance rat p464
Thanks to the availability of its genome sequence, and the promise of new genetically engineered strains, the rat is restoring its reputation as researchers' favourite lab animal. Alison Abbott hails a remarkable rodent.
Alison Abbott
doi:10.1038/428464a
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Correspondence
Ancient frog could spearhead conservation efforts p467
Newly discovered, this unique creature is already under threat from dam projects.
Ramesh K. Aggarwal
doi:10.1038/428467a
Diversity project takes time but reaps rewards p467
Small change p467
Irrelevance, buzzwords, coffee: it's the virtual PI p467
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Books and Arts
Power to the people p469
An analysis of the problems caused by an increasing energy demand.
doi:10.1038/428469a
Autistic genius? p470
doi:10.1038/428470a
Science in culture p471
The German Hygiene Museum in Dresden is reopening its doors.
Alison Abbott
doi:10.1038/428471a
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Essay
ConceptTurning down, but not off p473
Neuroprotection requires a paradigm shift in drug development.
Stuart A. Lipton
doi:10.1038/428473a
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News and Views
ゲノム解読：三つよれば文殊の知恵
Genome sequencing: Three's company p475
Publication of the rat genome sequence will not only advance physiological studies in this paragon of laboratory animals, but also greatly enhance the power of comparative research into mammalian genomes.
Kerstin Lindblad-Toh
doi:10.1038/428475a
地球科学：地球深部の裏面史
Earth science: Inside history in depth p476
The history of how Earth's interior evolved, and how it accounts for many aspects of our planet's behaviour, remains largely unwritten. Taking water into account could well help to explain a great deal more.
David Stevenson
doi:10.1038/428476a
昆虫学：厄介な時代のチョウ
Entomology: Butterflies at that awkward age p477
Beautifully preserved specimens of butterflies from the Caribbean, caught maybe in the act of egg-laying some 20 million years ago, provide welcome grist to the mill of debate about butterfly history.
Dick Vane-Wright
doi:10.1038/428477a
進化生物学：再び目覚めたシダ類
Evolutionary biology: Ferns reawakened p480
The principle of the evolutionary cul-de-sac is commonly invoked to explain the apparent lingering existence of once-diverse groups of organisms. Maybe that principle itself has had its day.
Torsten Eriksson
doi:10.1038/428480a
ナノ物理学：ナノチューブ磁気モーメントの決定的瞬間
Nanoscale physics: Big moment for nanotubes p481
Obituary: J. Beverley Oke (1928–2004) p483
News and views in brief p484
doi:10.1038/428484a
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Brief Communications
Gene regulation: Ancient microRNA target sequences in plants p485
A gene-regulation mechanism in plants predates the emergence of flowering species.
Sandra K. Floyd and John L. Bowman
doi:10.1038/428485a
First paragraph | Full Text | PDF (243K) | Supplementary information
Medical genetics: A marker for Stevens–Johnson syndrome p486
Wen-Hung Chung, Shuen-Iu Hung, Hong-Shang Hong, Mo-Song Hsih, Li-Cheng Yang, Hsin-Chun Ho, Jer-Yuarn Wu and Yuan-Tsong Chen
doi:10.1038/428486a
First paragraph | Full Text | PDF (103K) | Supplementary information
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Brief Communications Arising
Tumour suppression: Disruption of HAUSP gene stabilizes p53
Jordan M. Cummins, Carlo Rago, Manu Kohli, Kenneth W. Kinzler, Christoph Lengauer and Bert Vogelstein
doi:10.1038/nature02501
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Review
材料：生物学および医学分野に適した材料の設計
Designing materials for biology and medicine p487
Robert Langer and David A. Tirrell
doi:10.1038/nature02388
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Articles
遺伝：Brown Norwayラットのゲノム配列は哺乳類進化に関する考察をもたらす
Genome sequence of the Brown Norway rat yields insights into mammalian evolution p493
Rat Genome Sequencing Project Consortium
doi:10.1038/nature02426
日本語要約 | Full Text | PDF (1,215K) | Supplementary information
遺伝：ヒト13番染色体のDNA塩基配列とその解析
The DNA sequence and analysis of human chromosome 13 p522
A. Dunham, L. H. Matthews, J. Burton, J. L. Ashurst, K. L. Howe, K. J. Ashcroft, D. M. Beare, D. C. Burford, S. E. Hunt, S. Griffiths-Jones, M. C. Jones, S. J. Keenan, K. Oliver, C. E. Scott, R. Ainscough, J. P. Almeida, K. D. Ambrose, D. T. Andrews, R. I. S. Ashwell, A. K. Babbage, C. L. Bagguley, J. Bailey, R. Bannerjee, K. F. Barlow, K. Bates, H. Beasley, C. P. Bird, S. Bray-Allen, A. J. Brown, J. Y. Brown, W. Burrill, C. Carder, N. P. Carter, J. C. Chapman, M. E. Clamp, S. Y. Clark, G. Clarke, C. M. Clee, S. C. M. Clegg, V. Cobley, J. E. Collins, N. Corby, G. J. Coville, P. Deloukas, P. Dhami, I. Dunham, M. Dunn, M. E. Earthrowl, A. G. Ellington, L. Faulkner, A. G. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, J. G. R. Gilbert, C. J. Gilson, J. Ghori, D. V. Grafham, S. M. Gribble, C. Griffiths, R. E. Hall, S. Hammond, J. L. Harley, E. A. Hart, P. D. Heath, P. J. Howden, E. J. Huckle, P. J. Hunt, A. R. Hunt, C. Johnson, D. Johnson, M. Kay, A. M. Kimberley, A. King, G. K. Laird, C. J. Langford, S. Lawlor, D. A. Leongamornlert, D. M. Lloyd, C. Lloyd, J. E. Loveland, J. Lovell, S. Martin, M. Mashreghi-Mohammadi, S. J. McLaren, A. McMurray, S. Milne, M. J. F. Moore, T. Nickerson, S. A. Palmer, A. V. Pearce, A. I. Peck, S. Pelan, B. Phillimore, K. M. Porter, C. M. Rice, S. Searle, H. K. Sehra, R. Shownkeen, C. D. Skuce, M. Smith, C. A. Steward, N. Sycamore, J. Tester, D. W. Thomas, A. Tracey, A. Tromans, B. Tubby, M. Wall, J. M. Wallis, A. P. West, S. L. Whitehead, D. L. Willey, L. Wilming, P. W. Wray, M. W. Wright, L. Young, A. Coulson, R. Durbin, T. Hubbard, J. E. Sulston, S. Beck, D. R. Bentley, J. Rogers and M. T. Ross
doi:10.1038/nature02379
遺伝：ヒト19番染色体のDNA塩基配列とその生物学的性質
The DNA sequence and biology of human chromosome 19 p529
Jane Grimwood, Laurie A. Gordon, Anne Olsen, Astrid Terry, Jeremy Schmutz, Jane Lamerdin, Uffe Hellsten, David Goodstein, Olivier Couronne, Mary Tran-Gyamfi, Andrea Aerts, Michael Altherr, Linda Ashworth, Eva Bajorek, Stacey Black, Elbert Branscomb, Sean Caenepeel, Anthony Carrano, Chenier Caoile, Yee Man Chan, Mari Christensen, Catherine A. Cleland, Alex Copeland, Eileen Dalin, Paramvir Dehal, Mirian Denys, John C. Detter, Julio Escobar, Dave Flowers, Dea Fotopulos, Carmen Garcia, Anca M. Georgescu, Tijana Glavina, Maria Gomez, Eidelyn Gonzales, Matthew Groza, Nancy Hammon, Trevor Hawkins, Lauren Haydu, Isaac Ho, Wayne Huang, Sanjay Israni, Jamie Jett, Kristen Kadner, Heather Kimball, Arthur Kobayashi, Vladimer Larionov, Sun-Hee Leem, Frederick Lopez, Yunian Lou, Steve Lowry, Stephanie Malfatti, Diego Martinez, Paula McCready, Catherine Medina, Jenna Morgan, Kathryn Nelson, Matt Nolan, Ivan Ovcharenko, Sam Pitluck, Martin Pollard, Anthony P. Popkie, Paul Predki, Glenda Quan, Lucia Ramirez, Sam Rash, James Retterer, Alex Rodriguez, Stephanine Rogers, Asaf Salamov, Angelica Salazar, Xinwei She, Doug Smith, Tom Slezak, Victor Solovyev, Nina Thayer, Hope Tice, Ming Tsai, Anna Ustaszewska, Nu Vo, Mark Wagner, Jeremy Wheeler, Kevin Wu, Gary Xie, Joan Yang, Inna Dubchak, Terrence S. Furey, Pieter DeJong, Mark Dickson, David Gordon, Evan E. Eichler, Len A. Pennacchio, Paul Richardson, Lisa Stubbs, Daniel S. Rokhsar, Richard M. Myers, Edward M. Rubin and Susan M. Lucas
doi:10.1038/nature02399
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Letters to Nature
物理：カーボンナノチューブの電子軌道磁気モーメントの決定
Determination of electron orbital magnetic moments in carbon nanotubes p536
E. D. Minot, Yuval Yaish, Vera Sazonova and Paul L. McEuen
doi:10.1038/nature02425
日本語要約 | Full Text | PDF (393K)
工学：強磁性半導体構造における電流に誘起された磁壁スイッチング
Current-induced domain-wall switching in a ferromagnetic semiconductor structure p539
M. Yamanouchi, D. Chiba, F. Matsukura and H. Ohno
doi:10.1038/nature02441
日本語要約 | Full Text | PDF (451K)
材料：ダイヤモンドにおける超伝導
Superconductivity in diamond p542
E. A. Ekimov, V. A. Sidorov, E. D. Bauer, N. N. Mel'nik, N. J. Curro, J. D. Thompson and S. M. Stishov
doi:10.1038/nature02449
日本語要約 | Full Text | PDF (278K)
地震：負の体積変化を持つ脱水脆化によるやや深発地震の断層形成
Intermediate-depth earthquake faulting by dehydration embrittlement with negative volume change p545
Haemyeong Jung, Harry W. Green II and Larissa F. Dobrzhinetskaya
doi:10.1038/nature02412
日本語要約 | Full Text | PDF (409K)
海洋：鉄が引き起こした亜寒帯における植物プランクトンブルームの衰退と行方
The decline and fate of an iron-induced subarctic phytoplankton bloom p549
Philip W. Boyd, Cliff S. Law, C.S. Wong, Yukihiro Nojiri, Atsushi Tsuda, Maurice Levasseur, Shigenobu Takeda, Richard Rivkin, Paul J. Harrison, Robert Strzepek, Jim Gower, R. Mike McKay, Edward Abraham, Mike Arychuk, Janet Barwell-Clarke, William Crawford, David Crawford, Michelle Hale, Koh Harada, Keith Johnson, Hiroshi Kiyosawa, Isao Kudo, Adrian Marchetti, William Miller, Joe Needoba, Jun Nishioka, Hiroshi Ogawa, John Page, Marie Robert, Hiroaki Saito, Akash Sastri, Nelson Sherry, Tim Soutar, Nes Sutherland, Yosuke Taira, Frank Whitney, Shau-King Emmy Wong and Takeshi Yoshimura
doi:10.1038/nature02437
進化：シダ類は被子植物の陰で多様化した
Ferns diversified in the shadow of angiosperms p553
Harald Schneider, Eric Schuettpelz, Kathleen M. Pryer, Raymond Cranfill, Susana Magallón and Richard Lupia
doi:10.1038/nature02361
心理：自然的な顔のカテゴリーに対する順応
Adaptation to natural facial categories p557
Michael A. Webster, Daniel Kaping, Yoko Mizokami and Paul Duhamel
doi:10.1038/nature02420
日本語要約 | Full Text | PDF (386K)
免疫：マウスでSARSコロナウイルス中和と感染防御免疫を誘発するDNAワクチン
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice p561
Zhi-yong Yang, Wing-pui Kong, Yue Huang, Anjeanette Roberts, Brian R. Murphy, Kanta Subbarao and Gary J. Nabel
doi:10.1038/nature02463
発生：キイロショウジョウバエ卵巣で分化中の生殖細胞は機能を持った幹細胞に逆戻りできる
Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries p564
Toshie Kai and Allan Spradling
doi:10.1038/nature02436
生化学：AMPキナーゼは視床下部のホルモンと栄養シグナルに応答して摂食を制御する
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus p569
Yasuhiko Minokoshi, Thierry Alquier, Noboru Furukawa, Young-Bum Kim, Anna Lee, Bingzhong Xue, James Mu, Fabienne Foufelle, Pascal Ferré, Morris J. Birnbaum, Bettina J. Stuck and Barbara B. Kahn
doi:10.1038/nature02440
生理：1個の細菌における分子ノイズと行動の可変性
From molecular noise to behavioural variability in a single bacterium p574
Ekaterina Korobkova, Thierry Emonet, Jose M. G. Vilar, Thomas S. Shimizu and Philippe Cluzel
doi:10.1038/nature02404
生化学：筋肉のミオシンモーターは高負荷ではワーキングストロークが小さくかつ遅くなる
The myosin motor in muscle generates a smaller and slower working stroke at higher load p578
Massimo Reconditi, Marco Linari, Leonardo Lucii, Alex Stewart, Yin-Biao Sun, Peter Boesecke, Theyencheri Narayanan, Robert F. Fischetti, Tom Irving, Gabriella Piazzesi, Malcolm Irving and Vincenzo Lombardi
doi:10.1038/nature02380
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Careers and Recruitment
Career View
Naturejobs
ProspectsExploring careers p583
Careers and Recruitment
Changing of the guard p584
Opportunities in bioinformatics once abounded for the self-taught and industrially minded, but employers are now turning towards the formally trained and academics. Myrna Watanabe reports.
Myrna Watanabe
doi:10.1038/nj6982-584a
Career View
