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Nature 428, 382 (25 March 2004) | doi:10.1038/428382a

Signal processing:  Neural coding by correlation?

Arun V. Holden1

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Noise limits the efficiency of information transfer. But correlations of the intervals between signal pulses can reduce low-frequency noise and thereby increase the transfer of information.

A nerve cell is an example of a system whose excitation codes and transmits dynamic information. When a stimulus is above a given threshold, the neuron responds by generating an action potential, so that over time it fires irregular sequences of all-or-nothing spike responses.

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