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Nature 428, 267-269 (18 March 2004) | doi:10.1038/428267a
Cancer: Survival pathways meet their end
Frank McCormick1
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Abstract
Conventional chemotherapeutic approaches to treating tumours can be hit-and-miss. One way to ensure successful treatment may be to go for the jugular of cancer-cell survival signalling as well.
Chemotherapy uses powerful drugs designed to induce cancer cells to commit suicide. So why don't all tumours succumb to these drugs?
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