Table of contents
Volume 427 Number 6974 pp471-570
Editorials
Defeated but not deterred p471
Animal-rights protesters have helped to end plans for a primate research centre at the University of Cambridge. But despite the activists' triumphant soundbites, their victory is unlikely to be repeated elsewhere.
doi:10.1038/427471a
Sound thinking p471
For city dwellers, maps of noise pollution are a good example of what science can do to improve quality of life.
doi:10.1038/427471b
News
Fear of human pandemic grows as bird flu sweeps through Asia p472
Alison Abbott and Helen Pearson
doi:10.1038/427472a
Drug suicide risks prompt call for FDA action p474
Erika Check
doi:10.1038/427474a
Europe urged to move on transgenic crop imports p474
Quirin Schiermeier
doi:10.1038/427474b
Bush's belt-tightening budget offers science slim pickings p475
Geoff Brumfiel
doi:10.1038/427475a
US budget p475
doi:10.1038/427475b
Suicide-inquiry fallout 'could gag' scientists p476
Jim Giles
doi:10.1038/427476a
Fusion meeting shelved as site decision slides p476
Declan Butler
doi:10.1038/427476b
Universities battle for extra funds in bid to boost quality p477
Quirin Schiermeier
doi:10.1038/427477a
Extinction meeting kicks off Japan's plans for networking p477
David Cyranoski
doi:10.1038/427477b
News Features
Noise management: Sound and vision p480
Computer simulations that paint Europe's cities in riotous colour are at the core of a bold plan to restore peace and quiet to a population driven to distraction by traffic noise. Declan Butler takes a tour.
doi:10.1038/427480a
Quantum gravity: Back to the future p482
From reruns of a nineteenth-century experiment performed with breathtaking precision, we may gain our first glimpses of the physics that lies beyond Einstein's theories of relativity. Philip Ball reports.
doi:10.1038/427482a
Correspondence
Fertilizer 'solution' could turn local problem global p485
Protecting soil and water from pollution may mean releasing more greenhouse gas.
David S. Reay
doi:10.1038/427485a
Framework reveals lack of basic-research funds p485
Carlos F. Ibanez
doi:10.1038/427485b
Working hard for the money p485
Mike Fainzilber
doi:10.1038/427485c
Pet breeding has a long and colourful history p485
Sophien Kamoun
doi:10.1038/427485d
Books and Arts
Racial realities or bombast? p487
When is it helpful to categorize people according to race?
Robert N. Proctor reviews Race: The Reality of Human Differences by Vincent Sarich and Frank Miele
doi:10.1038/427487a
Plotting the downfall of society p488
Joseph A. Tainter reviews Historical Dynamics: Why States Rise and Fall by Peter Turchin
doi:10.1038/427488a
Get connected p489
Joanne Baker reviews Me++: The Cyborg Self and the Networked City by William J. Mitchell
doi:10.1038/427489a
Spot the Milky Way p489
Alison Abbott
doi:10.1038/427489b
Essay
Turning pointsPrisoners of the dilemma p491
When mathematics and biology met on a mountain.
Martin A. Nowak
doi:10.1038/427491a
News and Views
Medicine: K is for koagulation p493
Comparative genetic linkage studies in rats, mice and humans have finally identified a key component of vitamin K metabolism that is targeted by the commonest anticoagulant drugs in use today.
J. Evan Sadler
doi:10.1038/427493a
Planetary science: Double trouble p494
A surprising number of the icy objects in the Kuiper belt exist in pairs, or binaries. A new model proposes that these two-body systems were created through three-body interactions.
Joseph A. Burns
doi:10.1038/427494a
Cell division: Guardian spirit blesses meiosis p495
During egg and sperm production, the two copies of a duplicated chromosome must be bound together until it is time for their separation. A protein that protects this chromosomal glue has now been discovered.
Robin Allshire
doi:10.1038/427495a
Nanomaterials: Jagged edge p497
Philip Ball
doi:10.1038/427497a
Inorganic chemistry: Ammonia transformed p498
Ammonia is produced industrially by combining nitrogen and hydrogen gas, catalysed over a solid iron surface. How about a catalytic reaction that could take place in solution? The first steps have now been taken.
Michael D. Fryzuk
doi:10.1038/427498a
Ion channels: Shake, rattle or roll? p499
Nerve transmission depends on voltage-gated ion-channel proteins, which in turn depend on the behaviour of a membrane domain called the voltage sensor. Therein lies the latest episode in a continuing story.
Robert O. Blaustein and Christopher Miller
doi:10.1038/427499a
100 and 50 years ago p499
doi:10.1038/427499b
Correction p500
doi:10.1038/427500a
News and views in brief p501
doi:10.1038/427501a
Brief Communications
Stress propagation: Getting to the bottom of a granular medium p503
A surprising resistance would be put up by sand grains hiding a buried treasure chest.
Matthew B. Stone, David P. Bernstein, Rachel Barry, Matthew D. Pelc, Yee-Kin Tsui and Peter Schiffer
doi:10.1038/427503a
First paragraph | Full Text | PDF (149K) | Supplementary information
Transgenic mice: Fat-1 mice convert n-6 to n-3 fatty acids p504
Jing X. Kang, Jingdong Wang, Lin Wu and Zhao B. Kang
doi:10.1038/427504a
First paragraph | Full Text | PDF (144K)
Articles
Mixing, volatile loss and compositional change during impact-driven accretion of the Earth p505
Alex N. Halliday
doi:10.1038/nature02275
Abstract | Full Text | PDF (247K)
The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis p510
Tomoya S. Kitajima, Shigehiro A. Kawashima and Yoshinori Watanabe
doi:10.1038/nature02312
Abstract | Full Text | PDF (815K) | Supplementary information
See also: News and Views by Allshire
Letters to Nature
The formation of Kuiper-belt binaries through exchange reactions p518
Yoko Funato, Junichiro Makino, Piet Hut, Eiichiro Kokubo and Daisuke Kinoshita
doi:10.1038/nature02323
First paragraph | Full Text | PDF (315K)
See also: News and Views by Burns
Statistical mechanics of a gas-fluidized particle p521
R. P. Ojha, P.-A. Lemieux, P. K. Dixon, A. J. Liu and D. J. Durian
doi:10.1038/nature02294
First paragraph | Full Text | PDF (340K) | Supplementary information
A route to high surface area, porosity and inclusion of large molecules in crystals p523
Hee K. Chae, Diana Y. Siberio-Pérez, Jaheon Kim, YongBok Go, Mohamed Eddaoudi, Adam J. Matzger, Michael O'Keeffe and Omar M. Yaghi
doi:10.1038/nature02311
First paragraph | Full Text | PDF (304K) | Supplementary information
Hydrogenation and cleavage of dinitrogen to ammonia with a zirconium complex p527
Jaime A. Pool, Emil Lobkovsky and Paul J. Chirik
doi:10.1038/nature02274
First paragraph | Full Text | PDF (932K)
See also: News and Views by Fryzuk
Low-velocity zone atop the 410-km seismic discontinuity in the northwestern United States p530
Teh-Ru Alex Song, Don. V. Helmberger and Stephen P. Grand
doi:10.1038/nature02231
First paragraph | Full Text | PDF (2,699K) | Supplementary information
Mangroves enhance the biomass of coral reef fish communities in the Caribbean p533
Peter J. Mumby, Alasdair J. Edwards, J. Ernesto Arias-González, Kenyon C. Lindeman, Paul G. Blackwell, Angela Gall, Malgosia I. Gorczynska, Alastair R. Harborne, Claire L. Pescod, Henk Renken, Colette C. C. Wabnitz and Ghislane Llewellyn
doi:10.1038/nature02286
First paragraph | Full Text | PDF (226K) | Supplementary information
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2 p537
Simone Rost, Andreas Fregin, Vytautas Ivaskevicius, Ernst Conzelmann, Konstanze Hörtnagel, Hans-Joachim Pelz, Knut Lappegard, Erhard Seifried, Inge Scharrer, Edward G. D. Tuddenham, Clemens R. Müller, Tim M. Strom and Johannes Oldenburg
doi:10.1038/nature02214
First paragraph | Full Text | PDF (643K)
Identification of the gene for vitamin K epoxide reductase p541
Tao Li, Chun-Yun Chang, Da-Yun Jin, Pen-Jen Lin, Anastasia Khvorova and Darrel W. Stafford
doi:10.1038/nature02254
First paragraph | Full Text | PDF (218K)
Multiple transport modes of the cardiac Na+/Ca2+ exchanger p544
Tong Mook Kang and Donald W. Hilgemann
doi:10.1038/nature02271
First paragraph | Full Text | PDF (338K) | Supplementary information
A proton pore in a potassium channel voltage sensor reveals a focused electric field p548
Dorine M. Starace and Francisco Bezanilla
doi:10.1038/nature02270
First paragraph | Full Text | PDF (708K)
See also: News and Views by Blaustein & Miller
Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock p553
Chanseok Shin, Ying Feng and James L. Manley
doi:10.1038/nature02288
First paragraph | Full Text | PDF (451K) | Supplementary information
Molecular engineering of a backwards-moving myosin motor p558
Georgios Tsiavaliaris, Setsuko Fujita-Becker and Dietmar J. Manstein
doi:10.1038/nature02303
First paragraph | Full Text | PDF (236K) | Supplementary information
Crystal structure and mechanism of a bacterial fluorinating enzyme p561
Changjiang Dong, Fanglu Huang, Hai Deng, Christoph Schaffrath, Jonathan B. Spencer, David O'Hagan and James H. Naismith
doi:10.1038/nature02280
First paragraph | Full Text | PDF (332K)
Naturejobs
ProspectsCash incentives p567
Paul Smaglik
doi:10.1038/nj6974-567a
CAREERS AND RECRUITMENT
All systems go p568
If you can reassemble an organism from its component parts then a wealth of jobs may await you, says Hannah Hoag.
Hannah Hoag
doi:10.1038/nj6974-568a
Career View
Graduate Journal: Conference survival p570
Sidney Omelon
doi:10.1038/nj6974-570a
Nuts & Bolts p570
Deb Koen
doi:10.1038/nj6974-570b
Movers p570
doi:10.1038/nj6974-570c