FIGURE 1. VKORC1 mutations in individuals with VKCFD2 and WR.
From the following article:
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
Simone Rost, Andreas Fregin, Vytautas Ivaskevicius, Ernst Conzelmann, Konstanze Hörtnagel, Hans-Joachim Pelz, Knut Lappegard, Erhard Seifried, Inge Scharrer, Edward G. D. Tuddenham, Clemens R. Müller, Tim M. Strom and Johannes Oldenburg
Nature 427, 537-541(5 February 2004)
doi:10.1038/nature02214

Top, segregation of the Arg98Trp mutation in two families with VKCFD2 (left), and the electropherograms for a patient with a homozygous mutation (centre) and a control subject (right). Middle and bottom, the electropherograms for four WR patients with heterozygous mutations (85G
T, 134T
C, 172A
G, 383T
G) and a heterozygous Rw rat (416A
G).
