FIGURE 1. VKORC1 mutations in individuals with VKCFD2 and WR.

From the following article:

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Simone Rost, Andreas Fregin, Vytautas Ivaskevicius, Ernst Conzelmann, Konstanze Hörtnagel, Hans-Joachim Pelz, Knut Lappegard, Erhard Seifried, Inge Scharrer, Edward G. D. Tuddenham, Clemens R. Müller, Tim M. Strom and Johannes Oldenburg

Nature 427, 537-541(5 February 2004)

doi:10.1038/nature02214

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Top, segregation of the Arg98Trp mutation in two families with VKCFD2 (left), and the electropherograms for a patient with a homozygous mutation (centre) and a control subject (right). Middle and bottom, the electropherograms for four WR patients with heterozygous mutations (85G right arrow T, 134T right arrow C, 172A right arrow G, 383T right arrow G) and a heterozygous Rw rat (416A right arrow G).

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