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Editorials

Towards a German élite p271

A new government initiative to promote university development is a welcome attempt to stem the exodus of outstanding researchers from Germany. But it is also necessary to sustain deeper reform of the country's academic system.

doi:10.1038/427271a


Back to the Moon p271

Despite scientific casualties, sending people to the Moon is politically the best way forward for science in the long term.

doi:10.1038/427271b


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News

NASA's drive to revisit the Moon leaves no scope for Hubble p273

Tony Reichhardt

doi:10.1038/427273a


Bird flu sparks worldwide bid to prevent human pandemic p274

Alison Abbott & David Cyranoski

doi:10.1038/427274a


Director quits as cash cutbacks hit Californian labs p274

Rex Dalton

doi:10.1038/427274b


Feathers fly over welfare of hemmed-in hens p275

Laura Nelson

doi:10.1038/427275a


Ministers prepare to back neuroscience network p275

Declan Butler

doi:10.1038/427275b


Resignation threats add steel to French revolt p276

Declan Butler

doi:10.1038/427276a


Europe's researchers up in arms over clinical-trial rules p276

Alison Abbott

doi:10.1038/427276b


Health concerns prompt US review of exotic-pet trade p277

Erika Check

doi:10.1038/427277a


Telepathic charm seduces audience at paranormal debate p277

John Whitfield

doi:10.1038/427277b


News in brief p278

doi:10.1038/427278a


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News Features

Star quality p282

Japan's Nobel laureates have a celebrity status that outstrips anything seen by their contemporaries in North America or Europe. How have they balanced the desire to be a positive influence with the need to retain some privacy? David Cyranoski finds out.

doi:10.1038/427282a


Microbiology: Gut reaction p284

Consumers are stocking up on live yoghurts and fermented drinks that claim to improve health. But is there any science behind the marketing of these 'probiotic' products? Alison Abbott investigates.

doi:10.1038/427284a


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Correspondence

Milton and Galileo would back BMJ on free speech p287

Arguments, crazy ideas and open communication are the lifeblood of science.

Richard Smith

doi:10.1038/427287a


X-ray clues to viability of loop quantum gravity p287

Philip Kaaret

doi:10.1038/427287b


Return of bone archives is a loss to humanity p287

Neil Chalmers

doi:10.1038/427287c


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Commentary

The hole truth p289

What's news (and what's not) about the ozone hole.

doi:10.1038/427289a


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Books and Arts

The curious naturalist p293

Niko Tinbergen was one of the founders of ethology.

John Krebs reviews Niko's Nature by Hans Kruuk

doi:10.1038/427293a


Chemistry's bag of tricks p294

Bernadette Bensaude-Vincent reviews From Elements to Atoms: A History of Chemical Composition (Transaction 92-4)Robert Siegfried

doi:10.1038/427294a


Tuberculosis hits back p295

D. A. Mitchison reviews Return of the White Plague: Global Poverty and the 'New' Tuberculosis

doi:10.1038/427295a


Science in culture p296

John D. Barrow reviews

doi:10.1038/427296a


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Essay

Turning points

A meeting with Enrico Fermi p297

How one intuitive physicist rescued a team from fruitless research.

Freeman Dyson

doi:10.1038/427297a


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News and Views

Astronomy: A problem of distance p299

How far is the Pleiades star cluster from Earth? The latest measurement suggests that there is a problem with data from the Hipparcos satellite, which will have repercussions for estimating other astronomical distances.

Bohdan Paczynski

doi:10.1038/427299a


Cell division: Burning the spindle at both ends p300

Accurate transmission of the genome during cell division requires the physical separation of replicated chromosomes. The identities of two molecular motors needed to do the job in fruitflies are now revealed.

Rebecca W. Heald

doi:10.1038/427300a


Nanotechnology: Dreams of a hollow future p301

Carbon nanotubes have become familiar components in nanotechnology. Nanotubes made from inorganic materials are now on the rise, the latest creation being nanoscale tubes of a complex manganese oxide.

Luis Hueso & Neil Mathur

doi:10.1038/427301a


100 and 50 years ago p303

doi:10.1038/427303a


Psychology: Insight and the sleep committee p304

We all spend about a third of our lives asleep, an essential but seemingly unproductive state. Experimental evidence now emerges to support anecdotal evidence that sleep can stimulate creative thinking.

Pierre Maquet & Perrine Ruby

doi:10.1038/427304a


Biogeochemistry: Carbon budget in the black p305

A significant fraction of a common organic component of marine sediments has an unexpected source, providing a fresh context for studies of the global carbon cycle in oceanic and terrestrial settings.

Michael W. I. Schmidt

doi:10.1038/427305a


Virology: A class act p307

Membrane fusion occurs in many situations in living organisms — when certain viruses enter host cells, for instance. Three crystal structures shed light on the protein rearrangements that bring about such fusion.

Theodore S. Jardetzky & Robert A. Lamb

doi:10.1038/427307a


News and views in brief p309

doi:10.1038/427309a


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Brief Communications

Neuroplasticity: Changes in grey matter induced by training p311

Newly honed juggling skills show up as a transient feature on a brain-imaging scan.

Bogdan Draganski, Christian Gaser, Volker Busch, Gerhard Schuierer, Ulrich Bogdahn & Arne May

doi:10.1038/427311a


Animal behaviour: Cognitive bias and affective state p312

Emma J. Harding, Elizabeth S. Paul & Michael Mendl

doi:10.1038/427312a


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Articles

Structure of the dengue virus envelope protein after membrane fusion p313

Yorgo Modis, Steven Ogata, David Clements & Stephen C. Harrison

doi:10.1038/nature02165


Conformational change and protein–protein interactions of the fusion protein of Semliki Forest virus p320

Don L. Gibbons, Marie-Christine Vaney, Alain Roussel, Armelle Vigouroux, Brigid Reilly, Jean Lepault, Margaret Kielian & Félix A. Rey

doi:10.1038/nature02239


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Letters to Nature

A distance of 133–137 parsecs to the Pleiades star cluster p326

Xiaopei Pan, M. Shao & S. R. Kulkarni

doi:10.1038/nature02296


The microscopic nature of localization in the quantum Hall effect p328

S. Ilani, J. Martin, E. Teitelbaum, J. H. Smet, D. Mahalu, V. Umansky & A. Yacoby

doi:10.1038/nature02230


The role of increasing temperature variability in European summer heatwaves p332

Christoph Schär, Pier Luigi Vidale, Daniel Lüthi, Christoph Frei, Christian Häberli, Mark A. Liniger & Christof Appenzeller

doi:10.1038/nature02300


Reburial of fossil organic carbon in marine sediments p336

Angela F. Dickens, Yves Gélinas, Caroline A. Masiello, Stuart Wakeham & John I. Hedges

doi:10.1038/nature02299


Melting of iron at the physical conditions of the Earth's core p339

Jeffrey H. Nguyen & Neil C. Holmes

doi:10.1038/nature02248


Chicken welfare is influenced more by housing conditions than by stocking density p342

Marian Stamp Dawkins, Christl A. Donnelly & Tracey A. Jones

doi:10.1038/nature02226


Travelling waves in the occurrence of dengue haemorrhagic fever in Thailand p344

Derek A.T. Cummings, Rafael A. Irizarry, Norden E. Huang, Timothy P. Endy, Ananda Nisalak, Kumnuan Ungchusak & Donald S. Burke

doi:10.1038/nature02225


A primitive Y chromosome in papaya marks incipient sex chromosome evolution p348

Zhiyong Liu, Paul H. Moore, Hao Ma, Christine M. Ackerman, Makandar Ragiba, Qingyi Yu, Heather M. Pearl, Minna S. Kim, Joseph W. Charlton, John I. Stiles, Francis T. Zee, Andrew H. Paterson & Ray Ming

doi:10.1038/nature02228


Sleep inspires insight p352

Ullrich Wagner, Steffen Gais, Hilde Haider, Rolf Verleger & Jan Born

doi:10.1038/nature02223


Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 p355

Mehrdad Matloubian, Charles G. Lo, Guy Cinamon, Matthew J. Lesneski, Ying Xu, Volker Brinkmann, Maria L. Allende, Richard L. Proia & Jason G. Cyster

doi:10.1038/nature02284


The mitochondrial calcium uniporter is a highly selective ion channel p360

Yuriy Kirichok, Grigory Krapivinsky & David E. Clapham

doi:10.1038/nature02246


Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase p364

Gregory C. Rogers, Stephen L. Rogers, Tamara A. Schwimmer, Stephanie C. Ems-McClung, Claire E. Walczak, Ronald D. Vale, Jonathan M. Scholey & David J. Sharp

doi:10.1038/nature02256


The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes p370

Eulàlia de Nadal, Meritxell Zapater, Paula M. Alepuz, Lauro Sumoy, Glòria Mas & Francesc Posas

doi:10.1038/nature02258


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Naturejobs

Prospects

Shifting the balance p375

Paul Smaglik

doi:10.1038/nj6972-375a


CAREERS AND RECRUITMENT

Mapping opportunities p376

Scientists who can combine geographic information systems with satellite data are in demand in a variety of disciplines. Virginia Gewin gets her bearings.

Virginia Gewin

doi:10.1038/nj6972-376a


Career View

Graduate Journal: A tough challenge p378

Amber Jenkins

doi:10.1038/nj6972-378a


Scientists & Societies: Giving young European students a voice p378

Alexandre Urani, Raoul Tan, Renzo Rubele & Daniel Mietchen

doi:10.1038/nj6972-378b


Movers p378

doi:10.1038/nj6972-378c


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