Table of contents
Volume 427 Number 6971 pp181-270
Editorials
In praise of immigration p181
The United States is a nation of immigrants — and nowhere more so than in the lab. Yet officials of the federal government don't seem to recognize that the country's scientific strength depends in large part on foreign talent.
doi:10.1038/427181a
Don't fear the Robot Scientist p181
Contrary to first impressions, an automated system that designs its own experiments will benefit young molecular geneticists.
doi:10.1038/427181b
News
Robotic missions set to benefit as US takes aim at the Moon p183
Tony Reichhardt
doi:10.1038/427183a
Plans resurrected to raise Venice above the encroaching sea p184
Alison Abbott
doi:10.1038/427184a
Intelligence law draws fire over NSF security project p184
Geoff Brumfiel
doi:10.1038/427184b
Europe warned against research council p184
Jim Giles
doi:10.1038/427184c
Antibodies to SARS-like virus hint at repeated infections p185
Helen Pearson
doi:10.1038/427185a
India targets local HIV strain in test of AIDS vaccine p185
K. S. Jayaraman
doi:10.1038/427185b
Neglected diseases brought in from the cold p186
Alison Abbott
doi:10.1038/427186a
National park's sale of creationist book draws geologists' ire p186
Rex Dalton
doi:10.1038/427186b
Sandpit initiative digs deep to bring disciplines together p187
Jim Giles
doi:10.1038/427187a
Ethics accusations spark rapid reaction from NIH chief p187
Erika Check
doi:10.1038/427187b
News Feature
As one door closes... p190
Immigration controls introduced under the 'war on terror' are restricting the flow of foreign researchers into the United States. With other countries moving in on this pool of talent, will the balance of scientific power shift?
doi:10.1038/427190a
Correspondence
Scandals stem from the low priority of peer review p196
Good refereeing should be recognized and rewarded, with help from the journals.
Jean-Patrick Connerade
doi:10.1038/427196a
Eastern Europe: progress stifled by the old guard p196
Cezary Wójcik
doi:10.1038/427196b
Eastern Europe needs a competitive atmosphere p196
Juraj Gregan
doi:10.1038/427196c
Books and Arts
Warning of warming p197
How data and modelling led to predictions of climate change.
Stephen H. Schneider reviews The Discovery of Global Warming by Spencer R. Weart
doi:10.1038/427197a
The parenting gap p198
Abigail J. Stewart and Danielle LaVaque-Manty review Women in Science: Career Processes and Outcomes by Y. Xie and Kimberlee A. Shauman
doi:10.1038/427198a
The descent of man p199
Jennifer A. Marshall Graves reviews Adam's Curse: A Future Without Men by Bryan Sykes
doi:10.1038/427199a
Wildlife in watercolours p199
Mary Purton
doi:10.1038/427199b
Concepts
Tumour suppression: Putting on the brakes p201
Viewing cancer as a disease of cell differentiation rather than multiplication allows a redefinition of the role of oncogenes and tumour-suppressor genes.
Henry Harris
doi:10.1038/427201a
News and Views
Immunology: Protein surgery p203
Studies of human tumours and the immune system have revealed that cutting and pasting of proteins can generate new peptide variants. This startling finding has implications for both proteomics and immunity.
Hans-Georg Rammensee
doi:10.1038/427203a
Condensed-matter physics: Supersolid helium p204
Superfluids flow without resistance. It's hard to imagine, but quantum mechanically possible, that solids should do the same at low enough temperatures. Helium-4 might be the first known 'supersolid'.
John Beamish
doi:10.1038/427204a
Palaeontology: Lost children of the Cambrian p205
The initial flowering of animal life on Earth occurred during the Cambrian, some 540–490 million years ago. Fossil embryos from that time can provide clues about the origins of the major animal groups.
Graham E. Budd
doi:10.1038/427205a
100 and 50 years ago p205
doi:10.1038/427205b
Earth science: Keeping score on the core p207
Getting to the bottom of events at the boundary between Earth's core and mantle is fiendishly difficult. The latest analysis invokes evidence from an isotope of tungsten to conclude that the two do not interact.
Erik Hauri
doi:10.1038/427207a
Astronomy: Star maker p207
Alison Wright
doi:10.1038/427207b
Evolutionary biology: Our relative genetics p208
Data on the chimpanzee genome help in detecting differential selection on individual genes, and in judging whether normal microevolutionary processes are sufficient to account for human origins.
David Penny
doi:10.1038/427208a
News and views in brief p210
doi:10.1038/427210a
Brief Communications
Archaeology: A lion found in the Egyptian tomb of Maïa p211
Burial of a mummified lion at a dedicated site confirms this animal's once-sacred status.
Cécile Callou, Anaïck Samzun and Alain Zivie
doi:10.1038/427211a
First paragraph | Full Text | PDF (521K) | Supplementary information
Olfaction: Mosquito receptor for human-sweat odorant p212
Elissa A. Hallem, A. Nicole Fox, Laurence J. Zwiebel and John R. Carlson
doi:10.1038/427212a
First paragraph | Full Text | PDF (219K)
Climatology (communication arising): Rural land-use change and climate p213
Kevin E. Trenberth
doi:10.1038/427213a
First paragraph | Full Text | PDF (82K)
Climate (communication arising): Impact of land-use change on climate p213
Russell S. Vose, Thomas R. Karl, David R. Easterling, Claude N. Williams and Matthew J. Menne
doi:10.1038/427213b
First paragraph | Full Text | PDF (82K)
Climate (communication arising): Impact of land-use change on climate p214
Ming Cai and Eugenia Kalnay
doi:10.1038/427214a
First paragraph | Full Text | PDF (60K)
Article
Substrate twinning activates the signal recognition particle and its receptor p215
Pascal F. Egea, Shu-ou Shan, Johanna Napetschnig, David F. Savage, Peter Walter and Robert M. Stroud
doi:10.1038/nature02250
Abstract | Full Text | PDF (540K) | Supplementary information
Letters to Nature
An ultra-relativistic outflow from a neutron star accreting gas from a companion p222
Rob Fender, Kinwah Wu, Helen Johnston, Tasso Tzioumis, Peter Jonker, Ralph Spencer and Michiel van der Klis
doi:10.1038/nature02137
First paragraph | Full Text | PDF (364K)
Probable observation of a supersolid helium phase p225
E. Kim and M. H. W. Chan
doi:10.1038/nature02220
First paragraph | Full Text | PDF (236K)
See also: News and Views by Beamish
Partial order in the non-Fermi-liquid phase of MnSi p227
C. Pfleiderer, D. Reznik, L. Pintschovius, H. v. Löhneysen, M. Garst and A. Rosch
doi:10.1038/nature02232
First paragraph | Full Text | PDF (299K)
Observational evidence of a change in radiative forcing due to the indirect aerosol effect p231
Joyce E. Penner, Xiquan Dong and Yang Chen
doi:10.1038/nature02234
First paragraph | Full Text | PDF (986K)
Tungsten isotope evidence that mantle plumes contain no contribution from the Earth's core p234
Anders Scherstén, Tim Elliott, Chris Hawkesworth and Marc Norman
doi:10.1038/nature02221
First paragraph | Full Text | PDF (190K)
See also: News and Views by Hauri
Fossil embryos from the Middle and Late Cambrian period of Hunan, south China p237
Xi-ping Dong, Philip C. J. Donoghue, Hong Cheng and Jian-bo Liu
doi:10.1038/nature02215
First paragraph | Full Text | PDF (336K) | Supplementary information
See also: News and Views by Budd
Whole-lake carbon-13 additions reveal terrestrial support of aquatic food webs p240
Michael L. Pace, Jonathan J. Cole, Stephen R. Carpenter, James F. Kitchell, James R. Hodgson, Matthew C. Van de Bogert, Darren L. Bade, Emma S. Kritzberg and David Bastviken
doi:10.1038/nature02227
First paragraph | Full Text | PDF (214K) | Supplementary information
Bayesian integration in sensorimotor learning p244
Konrad P. Körding and Daniel M. Wolpert
doi:10.1038/nature02169
First paragraph | Full Text | PDF (270K)
Functional genomic hypothesis generation and experimentation by a robot scientist p247
Ross D. King, Kenneth E. Whelan, Ffion M. Jones, Philip G. K. Reiser, Christopher H. Bryant, Stephen H. Muggleton, Douglas B. Kell and Stephen G. Oliver
doi:10.1038/nature02236
First paragraph | Full Text | PDF (661K) | Supplementary information
Immune recognition of a human renal cancer antigen through post-translational protein splicing p252
Ken-ichi Hanada, Jonathan W. Yewdell and James C. Yang
doi:10.1038/nature02240
First paragraph | Full Text | PDF (734K) | Supplementary information
See also: News and Views by Rammensee
Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP p256
Sharon A. Matheny, Chiyuan Chen, Robert L. Kortum, Gina L. Razidlo, Robert E. Lewis and Michael A. White
doi:10.1038/nature02237
First paragraph | Full Text | PDF (320K) | Supplementary information
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1 p260
Sven-Eric Jordt, Diana M. Bautista, Huai-hu Chuang, David D. McKemy, Peter M. Zygmunt, Edward D. Högestätt, Ian D. Meng and David Julius
doi:10.1038/nature02282
First paragraph | Full Text | PDF (599K) | Supplementary information
Erratum: Structure and conserved RNA binding of the PAZ domain p265
Kelley S. Yan, Sherry Yan, Amjad Farooq, Arnold Han, Lei Zeng and Ming-Ming Zhou
doi:10.1038/nature02252
Corrigendum: Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis p265
Xue Li, Kenneth A. Ohgi, Jie Zhang, Anna Krones, Kevin T. Bush, Christopher K. Glass, Sanjay K. Nigam, Aneel K. Aggarwal, Richard Maas, David W. Rose and Michael G. Rosenfeld
doi:10.1038/nature02283
Naturejobs
ProspectsStarting the brain gain p267
Paul Smaglik
doi:10.1038/nj6971-267a
SPECIAL REPORT
Destressing in the geekosphere p268
Finding a balance in the daily grind requires creativity and a sense of play. Kendall Powell explores how lifestyle can complement science.
Kendall Powell
doi:10.1038/nj6971-268a
Career View
Graduate Journal: At the crossroads p270
Philipp Angerer
doi:10.1038/nj6971-270a
Bricks & Mortar: Lancaster Environment Centre p270
Paul Smaglik
doi:10.1038/nj6971-270b
Movers p270
doi:10.1038/nj6971-270c
