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Nature 427, 106-107 (8 January 2004) | doi:10.1038/427106a
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Stem cells: How to make eggs and sperm
M. Azim Surani1
Abstract
Embryonic stem cells can develop into many specialized cell types in culture dishes. It now seems that they can also generate primordial germ cells, which then go on to form sperm and eggs.
A fertilized egg is potentially immortal: this fusion of egg and sperm gives rise not only to a new individual, but also (theoretically at least) to an endless series of generations. Three groups now suggest that it is possible to generate both of these remarkable cells — known collectively as germ cells — in a culture dish.
- M. Azim Surani is at the Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.
Email: as10021@mole.bio.cam.ac.uk
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