Table of contents
Volume 427 Number 6970 pp87-180
Editorials
The red planet's big picture p87
Let's not get carried away with the images from NASA's Spirit rover, nor despair of Britain's silent Beagle 2. The best way to explore Mars is through a programme that builds patiently on each mission's successes and failures.
doi:10.1038/427087a
China and SARS: could do better p87
Has the world's most populous nation learnt the lessons of last year's SARS outbreak? Only partially, it seems.
doi:10.1038/427087b
News
Rover barks before Beagle as Mars success lifts NASA's spirits p89
Tony Reichhardt
doi:10.1038/427089a
Swift response greets return of SARS in China p89
David Cyranoski
doi:10.1038/427089b
Yucca review-board head quits in face of impartiality charges p90
Geoff Brumfiel
doi:10.1038/427090a
Safety concerns prompt US ban on dietary supplement p90
Jonathan Knight
doi:10.1038/427090b
Geneticists chip away at unruly data p91
Erika Check
doi:10.1038/427091a
Canadian prime minister makes science a priority p91
David Spurgeon
doi:10.1038/427091b
News Features
Hungarian science: Dreaming on the Danube p94
Can Budapest regain its status as one of Europe's scientific hubs? Perhaps, if the generation gap between Soviet-era scientists and young, westward-looking researchers can be bridged. Quirin Schiermeier reports.
doi:10.1038/427094a
Automatic archaeology p96
Digging in the dirt in search of clues to the past has churned up millions of pieces of pottery. Haim Watzman unearths the new technologies being developed to sift through them all.
doi:10.1038/427096a
Correspondence
Cooperation needed to increase fertilizer efficiency p99
Better use of nitrogen could provide more food and reduce the environmental impact.
M. M. Alley
doi:10.1038/427099a
Fertilizer: complex issue calls for informed debate p99
Mark B. David, Gregory F. McIsaac, Robert W. Howarth, Christine L. Goodale and Laurie E. Drinkwater
doi:10.1038/427099b
Fertilizer: no-till farming could reduce run-off p99
Anthony Trewavas
doi:10.1038/427099c
Books and Arts
When development goes wrong p101
Studying mutants helps our understanding of how we all take shape.
Peter Little reviews Mutants by Armand Marie Leroi
doi:10.1038/427101a
Watching the Earth move p102
Michael Matthews reviews Pendulum: Léon Foucault and the Triumph of Science by Amir D. Aczel
doi:10.1038/427102a
A glimpse inside the Sun p103
Jørgen Christensen-Dalsgaard reviews Sunquakes: Probing the Interior of the Sun by Jack B. Zirker
doi:10.1038/427103a
News and Views
A glass bead game p105
Microscopic glass beads coated with lipid membranes provide a sensitive detector of interactions between proteins and ligands. The changing spatial order of the array of beads in solution is the key.
Thomas M. Bayerl
doi:10.1038/427105a
Stem cells: How to make eggs and sperm p106
Embryonic stem cells can develop into many specialized cell types in culture dishes. It now seems that they can also generate primordial germ cells, which then go on to form sperm and eggs.
M. Azim Surani
doi:10.1038/427106a
Ecology: Clouded futures p107
Global warming is altering the distribution and abundance of plant and animal species. Application of a basic law of ecology predicts that many will vanish if temperatures continue to rise.
J. Alan Pounds and Robert Puschendorf
doi:10.1038/427107a
100 and 50 years ago p107
doi:10.1038/427107b
Astronomy: To catch a stellar thief p109
A supernova seen in 1993 defied explanation. Astronomers suspected the dying star had lost much of its hydrogen before the explosion. The discovery of a companion to this star suggests where that gas went...
Thomas Matheson
doi:10.1038/427109a
Cancer: Guarding the guardian? p110
The diversity of cellular stresses that activate the 'guardian of the genome' — p53 — begs the question of how these signals all converge on one protein. Perhaps the key to this integration is the nucleolus.
Henning F. Horn and Karen H. Vousden
doi:10.1038/427110a
Developmental biology: Asymmetric fixation p111
Computer simulations and laboratory experiments have shed light on how an asymmetric pattern of gene expression is fixed in vertebrate embryos — an early step towards asymmetric development of the internal organs.
Nick Monk
doi:10.1038/427111a
Plant development: The flowers that bloom in the spring p112
Christopher Surridge
doi:10.1038/427112a
News and views in brief p113
doi:10.1038/427113a
Brief Communications
Seismology: Explosive craters and soil liquefaction p115
Curious dry craters formed in the aftermath of a disastrous earthquake are explained.
Paul A. Rydelek and Martitia Tuttle
doi:10.1038/427115a
First paragraph | Full Text | PDF (149K)
Acoustics: Tuning of vocal tract resonance by sopranos p116
Elodie Joliveau, John Smith and Joe Wolfe
doi:10.1038/427116a
First paragraph | Full Text | PDF (57K)
Articles
Dating the rise of atmospheric oxygen p117
A. Bekker, H. D. Holland, P.-L. Wang, D. Rumble, III, H. J. Stein, J. L. Hannah, L. L. Coetzee and N. J. Beukes
doi:10.1038/nature02260
Abstract | Full Text | PDF (322K)
Notch activity acts as a sensor for extracellular calcium during vertebrate left–right determination p121
Ángel Raya, Yasuhiko Kawakami, Concepción Rodríguez-Esteban, Marta Ibañes, Diego Rasskin-Gutman, Joaquín Rodríguez-León, Dirk Büscher, José A. Feijó and Juan Carlos Izpisúa Belmonte
doi:10.1038/nature02190
Abstract | Full Text | PDF (511K) | Supplementary information
See also: News and Views by Monk
Letters to Nature
The massive binary companion star to the progenitor of supernova 1993J p129
Justyn R. Maund, Stephen J. Smartt, Rolf P. Kudritzki, Philipp Podsiadlowski and Gerard F. Gilmore
doi:10.1038/nature02161
First paragraph | Full Text | PDF (213K)
See also: News and Views by Matheson
An intense stratospheric jet on Jupiter p132
F. M. Flasar, V. G. Kunde, R. K. Achterberg, B. J. Conrath, A. A. Simon-Miller, C. A. Nixon, P. J. Gierasch, P. N. Romani, B. Bézard, P. Irwin, G. L. Bjoraker, J. C. Brasunas, D. E. Jennings, J. C. Pearl, M. D. Smith, G. S. Orton, L. J. Spilker, R. Carlson, S. B. Calcutt, P. L. Read, F. W. Taylor, P. Parrish, A. Barucci, R. Courtin, A. Coustenis, D. Gautier, E. Lellouch, A. Marten, R. Prangé, Y. Biraud, T. Fouchet, C. Ferrari, T. C. Owen, M. M. Abbas, R. E. Samuelson, F. Raulin, P. Ade, C. J. Césarsky, K. U. Grossman and A. Coradini
doi:10.1038/nature02142
First paragraph | Full Text | PDF (299K)
Hybridization of electronic states in quantum dots through photon emission p135
Khaled Karrai, Richard J. Warburton, Christian Schulhauser, Alexander Högele, Bernhard Urbaszek, Ewan J. McGhee, Alexander O. Govorov, Jorge M. Garcia, Brian D. Gerardot and Pierre M. Petroff
doi:10.1038/nature02109
First paragraph | Full Text | PDF (210K) | Supplementary information
Detection of molecular interactions at membrane surfaces through colloid phase transitions p139
Michael M. Baksh, Michal Jaros and Jay T. Groves
doi:10.1038/nature02209
First paragraph | Full Text | PDF (290K) | Supplementary information
See also: News and Views by Bayerl
Critically pressured free-gas reservoirs below gas-hydrate provinces p142
Matthew J. Hornbach, Demian M. Saffer and W. Steven Holbrook
doi:10.1038/nature02172
First paragraph | Full Text | PDF (271K)
Extinction risk from climate change p145
Chris D. Thomas, Alison Cameron, Rhys E. Green, Michel Bakkenes, Linda J. Beaumont, Yvonne C. Collingham, Barend F. N. Erasmus, Marinez Ferreira de Siqueira, Alan Grainger, Lee Hannah, Lesley Hughes, Brian Huntley, Albert S. van Jaarsveld, Guy F. Midgley, Lera Miles, Miguel A. Ortega-Huerta, A. Townsend Peterson, Oliver L. Phillips and Stephen E. Williams
doi:10.1038/nature02121
First paragraph | Full Text | PDF (128K) | Supplementary information
See also: News and Views by Pounds & Puschendorf
Derivation of embryonic germ cells and male gametes from embryonic stem cells p148
Niels Geijsen, Melissa Horoschak, Kitai Kim, Joost Gribnau, Kevin Eggan and George Q. Daley
doi:10.1038/nature02247
First paragraph | Full Text | PDF (415K)
See also: News and Views by Surani
T-cell priming by dendriticcells in lymph nodes occurs in three distinct phases p154
Thorsten R. Mempel, Sarah E. Henrickson and Ulrich H. von Andrian
doi:10.1038/nature02238
First paragraph | Full Text | PDF (420K) | Supplementary information
Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3 p159
Sibum Sung and Richard M. Amasino
doi:10.1038/nature02195
First paragraph | Full Text | PDF (392K)
Vernalization requires epigenetic silencing of FLC by histone methylation p164
Ruth Bastow, Joshua S. Mylne, Clare Lister, Zachary Lippman, Robert A. Martienssen and Caroline Dean
doi:10.1038/nature02269
First paragraph | Full Text | PDF (257K) | Supplementary information
Bcl10 activates the NF-
B pathway through ubiquitination of NEMO p167
Honglin Zhou, Ingrid Wertz, Karen O'Rourke, Mark Ultsch, Somasekar Seshagiri, Michael Eby, Wei Xiao and Vishva M. Dixit
doi:10.1038/nature02273
First paragraph | Full Text | PDF (369K) | Supplementary information
Vinculin activation by talin through helical bundle conversion p171
Tina Izard, Gwyndaf Evans, Robert A. Borgon, Christina L. Rush, Gerard Bricogne and Philippe R. J. Bois
doi:10.1038/nature02281
First paragraph | Full Text | PDF (312K) | Supplementary information
Erratum: Hydrocarbons and the evolution of human culture p175
Charles Hall, Pradeep Tharakan, John Hallock, Cutler Cleveland and Michael Jefferson
doi:10.1038/nature02217
Naturejobs
ProspectsTuning in to yourself p177
Paul Smaglik
doi:10.1038/nj6970-177a
POSTDOCS
Healthy limits p178
The US National Institutes of Health stipends are being used as de facto guidelines for postdoc salaries. But do institutions try to meet them? Karen Kreeger investigates.
Karen Kreeger
doi:10.1038/nj6970-178a
Career View
Graduate Journal: From biochemist to engineer p180
Sidney Omelon
doi:10.1038/nj6970-180a
Nuts & Bolts: Career journals p180
Deb Koen
doi:10.1038/nj6970-180b
Movers p180
doi:10.1038/nj6970-180c