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Nature 426, 780-781 (18 December 2003) | doi:10.1038/426780a

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Cell cycle: Passenger acrobatics

Toru Higuchi & Frank Uhlmann

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Chromosomal passenger proteins undergo spectacular changes in localization during cell division. We now have molecular insight into how and why these changes occur.

Of all the cellular proteins, chromosomal passengers display some of the most visually striking patterns of behaviour. These proteins associate with chromosomes as cells prepare to segregate them during nuclear division (mitosis).

  1. Toru Higuchi and Frank Uhlmann are in the Chromosome Segregation Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

Correspondence to: Frank Uhlmann Email: frank.uhlmann@cancer.org.uk