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Nature 426, 742 (18 December 2003) | doi:10.1038/426742b

'Reverse genetics' could offer forward-thinking flu vaccine

Helen Pearson

Health authorities are under renewed pressure to modernize influenza-vaccine production after an early surge in flu has highlighted shortfalls in the current jab.Concerns about the vaccine were raised after an early and sudden start to the influenza season in Europe and the United States in late October.