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Brief Communications
Nature 426, 620 (11 December 2003) | doi:10.1038/426620a
Open Innovation Challenges
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Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
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Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
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Gastroenterologist
- Florida Gastroenterology Practice
- Florida, USA
Postdoc
- Universitatsmedizin Gottingen
- Gottingen 37099 Deutschland
Genetics: Influence of TOR kinase on lifespan in C. elegans
Tibor Vellai1, Krisztina Takacs-Vellai1, Yue Zhang1, Attila L. Kovacs2, László Orosz3,4 & Fritz Müller1
Abstract
The group of enzymes known as TOR (for 'target of rapamycin') kinases regulates cell growth and proliferation in response to nutrients and hormone-dependent mitogenic signals1, 2. Here we show that TOR deficiency in the nematode Caenorhabditis elegans more than doubles its natural lifespan. This new function for TOR signalling in ageing control may represent a link between nutrition, metabolism and longevity.
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