Table of contents


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Editorials

Facing up to endangered apes p369

A United Nations-sponsored meeting in Paris this week will indicate whether humanity has the wherewithal to save our closest cousins in the animal kingdom from extinction.

doi:10.1038/426369a


Eastern promise p369

Untapped scientific potential to the east offers short-term challenges for the European Union, but will strengthen it in the end.

doi:10.1038/426369b


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News

State department woos weapons researchers in bid to rebuild Iraq p371

Geoff Brumfiel

doi:10.1038/426371a


Germany puts faith in big guns as science ministry feels pinch p372

Quirin Schiermeier

doi:10.1038/426372a


GloFish casts light on murky policing of transgenic animals p372

Jonathan Knight

doi:10.1038/426372b


Promega changes tack in battle over patent p373

Jonathan Knight

doi:10.1038/426373a


US draws up plans to tackle autism p373

Emily Singer

doi:10.1038/426373b


University buildings named on shaky ground p374

Rex Dalton

doi:10.1038/426374a


Russian claims first in magnetic imaging p375

Bryon MacWilliams

doi:10.1038/426375a


US on sidelines as China prepares for satellite launch p375

Tony Reichhardt

doi:10.1038/426375b


News in brief p376

doi:10.1038/426376a


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News Features

Fish farming: Eat your veg p378

With fish farming on the rise, researchers are seeking ways to make aquaculture more sustainable. One solution may mean turning carnivorous fish into vegetarians. Kendall Powell gets a taste of the future.

Kendall Powell

doi:10.1038/426378a


Space science: Unstoppable force p380

After 40 years in development, and some $650 million of NASA funds, Gravity Probe B is almost ready to launch. Would Einstein, whose theories it is about to test, have approved? Tony Reichhardt reports.

Tony Reichhardt

doi:10.1038/426380a


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Correspondence

Filling the gap between knowing and doing p383

Research into delivery systems is needed to translate knowledge into improved health.

Tikki Pang

doi:10.1038/426383a


Open access: the JCI has already shown it works p383

Ajit Varki

doi:10.1038/426383b


Aircraft give a new view of jellyfish behaviour p383

Graeme C. Hays, Jon. D. R. Houghton, Tom Doyle and John Davenport

doi:10.1038/426383c


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Books and Arts

Fuzzy vision p385

A dark view of a future where the lines of self are blurred.

doi:10.1038/426385a


Jazzing up neuroscience p386

doi:10.1038/426386a


Looking for a new home? p386

doi:10.1038/426386b


Exhibition: Seeing the light p387

Colin Martin

doi:10.1038/426387a


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Concepts

Scientist: Four golden lessons p389

Steven Weinberg

doi:10.1038/426389a


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News and Views

言語学:生命の樹と言語の樹

Linguistics: Trees of life and of language p391

The dating of ancient languages by a technique called glottochronology is undergoing a revival, stimulated by the computational and statistical methods used to tease out evolutionary relationships in biology.

David B. Searls

doi:10.1038/426391a


細胞生物学:記憶のおかげ

Cell biology: Thanks for the memory p392

In response to a transient hormonal cue, a developing egg commits irreversibly to a mature state. Surprisingly, this irreversible switch is composed of intrinsically reversible components.

Jill C. Sible

doi:10.1038/426392a


惑星科学:カイパーベルトに運び出す

Planetary science: Conveyed to the Kuiper belt p393

The small icy bodies that make up the Kuiper belt are the most distant objects known in the Solar System. A consistent picture is now emerging which suggests that these objects formed much closer to the Sun.

Rodney Gomes

doi:10.1038/426393a


比較ゲノミクス:2匹の線虫は1匹に勝る

Comparative genomics: Two worms are better than one p395

The genome of the microscopic worm Caenorhabditis briggsae has been sequenced, and shows some remarkable differences from the genome of the better known — and physically similar — C. elegans.

Mark Blaxter

doi:10.1038/426395a


天文学:遠い宇宙で輝く灯火

Astronomy: Beacons in the distant cosmos p397

Gamma-ray bursts are the brightest and most distant explosions in the Universe. A convincing body of evidence now links these bursts to supernovae, but there is still more to learn about their origins.

Luigi Piro

doi:10.1038/426397a


100 and 50 years ago p397

doi:10.1038/426397b


構造生物学:光合成に関する

Structural biology: Dual approach to a light problem p399

The structure of the last of the major pigment-containing protein complexes involved in photosynthesis is now revealed. The details complete our picture of electron shuttling in this vital process.

Werner Kühlbrandt

doi:10.1038/426399a


地球科学:差がつくのが超遅い海嶺

Earth science: The ultraslow difference p401

The speed at which mid-ocean ridges grind out new ocean floor varies considerably. The slowest-spreading ridges are especially tough to study — but the latest data show that they are especially intriguing.

Jason Phipps Morgan

doi:10.1038/426401a


News and views in brief p402

doi:10.1038/426402a


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Brief Communications

Pharmacology: Uncoupling the agony from ecstasy p403

A mitochondrial protein may mediate a dangerous side-effect of some recreational drugs.

Edward M. Mills, Matthew L. Banks, Jon E. Sprague and Toren Finkel

doi:10.1038/426403a


Photonic crystals: Imaging by flat lens using negative refraction p404

Patanjali V. Parimi, Wentao T. Lu, Plarenta Vodo and Srinivas Sridhar

doi:10.1038/426404a


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Articles

地球:拡大速度の極めて遅い種類の海嶺

An ultraslow-spreading class of ocean ridge p405

Henry J. B. Dick, Jian Lin and Hans Schouten

doi:10.1038/nature02128


生化学:シトクロムb6f複合体に含まれる異例のヘム

An atypical haem in the cytochrome b6f complex p413

David Stroebel, Yves Choquet, Jean-Luc Popot and Daniel Picot

doi:10.1038/nature02155


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Letters to Nature

宇宙:海王星の移動中に起こった天体の外側への輸送によるカイパーベルトの形成

The formation of the Kuiper belt by the outward transport of bodies during Neptune's migration p419

Harold F. Levison and Alessandro Morbidelli

doi:10.1038/nature02120


工学:光学格子による微小流体選別

Microfluidic sorting in an optical lattice p421

M. P. MacDonald, G. C. Spalding and K. Dholakia

doi:10.1038/nature02144


工学:圧力誘起流による「バロプラスチック」の低温加工

Low-temperature processing of 'baroplastics' by pressure-induced flow p424

Juan A. Gonzalez-Leon, Metin H. Acar, Sang-Woog Ryu, Anne-Valérie G. Ruzette and Anne M. Mayes

doi:10.1038/nature02140


材料:高速イオン伝導性を示す結晶性無機カルコゲナイドの合成設計

Synthetic design of crystalline inorganic chalcogenides exhibiting fast-ion conductivity p428

Nanfeng Zheng, Xianhui Bu and Pingyun Feng

doi:10.1038/nature02159


地球:爆発的火山活動はマグマ破砕の必然的な結果ではない可能性がある

Explosive volcanism may not be an inevitable consequence of magma fragmentation p432

Helge M. Gonnermann and Michael Manga

doi:10.1038/nature02138


言語:言語の系統樹の分岐年代は、インド‐ヨーロッパ語族の起源がアナトリアであることを裏づけている

Language-tree divergence times support the Anatolian theory of Indo-European origin p435

Russell D. Gray and Quentin D. Atkinson

doi:10.1038/nature02029


生態:河川メソコスムにおける生態系過程への微生物バイオフィルムの寄与

Contributions of microbial biofilms to ecosystem processes in stream mesocosms p439

Tom J. Battin, Louis A. Kaplan, J. Denis Newbold and Claude M. E. Hansen

doi:10.1038/nature02152


聴覚:聴覚皮質の同調とスパイクタイミングの尖鋭化を生み出す均衡的抑制

Balanced inhibition underlies tuning and sharpens spike timing in auditory cortex p442

Michael Wehr and Anthony M. Zador

doi:10.1038/nature02116


発生:軸極性と胚葉分離の進化における核内β-カテニンの進化的に古い役割

An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation p446

Athula H. Wikramanayake, Melanie Hong, Patricia N. Lee, Kevin Pang, Christine A. Byrum, Joanna M. Bince, Ronghui Xu and Mark Q. Martindale

doi:10.1038/nature02113


医学:アンギオテンシン変換酵素2はSARSコロナウイルスに対する機能的受容体である

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus p450

Wenhui Li, Michael J. Moore, Natalya Vasilieva, Jianhua Sui, Swee Kee Wong, Michael A. Berne, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, Thomas C. Greenough, Hyeryun Choe and Michael Farzan

doi:10.1038/nature02145


医学:ZAP-70遺伝子の変異による胸腺T細胞選択の変化はマウスに自己免疫性関節炎を引き起こす

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice p454

Noriko Sakaguchi, Takeshi Takahashi, Hiroshi Hata, Takashi Nomura, Tomoyuki Tagami, Sayuri Yamazaki, Toshiko Sakihama, Takaji Matsutani, Izumi Negishi, Syuichi Nakatsuru and Shimon Sakaguchi

doi:10.1038/nature02119


発生:正のフィードバックに基づく双安定の「記憶モジュール」が細胞運命決定を支配する

A positive-feedback-based bistable 'memory module' that governs a cell fate decision p460

Wen Xiong and James E. Ferrell, Jr

doi:10.1038/nature02089


生化学:Drosophila Argonaute 2 PAZドメインの構造と核酸結合

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain p465

Andreas Lingel, Bernd Simon, Elisa Izaurralde and Michael Sattler

doi:10.1038/nature02123


生化学:PAZドメインの構造とよく保存されたRNAとの結合

Structure and conserved RNA binding of the PAZ domain p469

Kelley S. Yan, Sherry Yan, Amjad Farooq, Arnold Han, Lei Zeng and Ming-Ming Zhou

doi:10.1038/nature02129


Addendum: Specific cytotoxic T cells eliminate cells producing neutralizing antibodies p474

Oliver Planz, Peter Seiler, Hans Hengartner and Rolf M. Zinkernagel

doi:10.1038/nature02146


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New on the Market

Genomics and proteomics p475

Variations on the theme of DNA and the proteins it makes.

doi:10.1038/426375a


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Naturejobs

Prospects

Home-grown success p477

Paul Smaglik

doi:10.1038/nj6965-477a


CAREERS AND RECRUITMENT

Small world, big hopes p478

Nanoscience is fragmenting into tinier pieces, but there are great expectations everywhere. Myrna Watanabe investigates.

Myrna Watanabe

doi:10.1038/nj6965-478a


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