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Nature 426, 395-396 (27 November 2003) | doi:10.1038/426395a
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Comparative genomics: Two worms are better than one
Mark Blaxter1
Abstract
The genome of the microscopic worm Caenorhabditis briggsae has been sequenced, and shows some remarkable differences from the genome of the better known — and physically similar — C. elegans.
In the early 1960s, when biologist Sydney Brenner was searching for a new model organism with which to study animal development and neurobiology, he screened a wide range of invertebrate species and chose the nematode Caenorhabditis elegans because it is easy to culture and transparent at all stages of its life cycle1. This small worm is now famous, not least for being the first animal to have its whole genome sequenced2.
- Mark Blaxter is in the School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK.
Email: mark.blaxter@ed.ac.uk
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