Table of contents


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Editorial

Towards a clean collider p105

The high-energy physics community has grand plans to probe deeper into the structure of matter and space-time. The proposal for a multinational linear collider merits strong support.

doi:10.1038/426105a


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News

Consumers warned that time is not yet ripe for nutrition profiling p107

Erika Check

doi:10.1038/426107a


Antarctic research frozen out of Japan's budget plans p108

Keiko Kandachi

doi:10.1038/426108a


US reveals physics wish-list in bid for scientific frontier p108

Geoff Brumfiel

doi:10.1038/426108b


Bone archives face prospect of dispersal p109

Jim Giles

doi:10.1038/426109a


African states pledge increased spending on research p109

Michael Cherry

doi:10.1038/426109b


Magnetic effect sends physicists into a spin p110

Geoff Brumfiel

doi:10.1038/426110a


Geologists call for desalination of Gaza Strip's water p110

Betsy Mason

doi:10.1038/426110b


Primatologist rocks Gibraltar by quitting over macaque cull p111

Quirin Schiermeier

doi:10.1038/426111a


Italy's proposal for technology institute riles researchers p111

Alison Abbott

doi:10.1038/426111b


News in brief p112

doi:10.1038/426112a


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News Features

Drugs in sport: No dope p114

Don Catlin's lab has struck a major blow against drug abuse in athletics, by developing a test for a shadowy 'designer steroid'. Jonathan Knight visits the scientists who are striving to keep sport clean.

doi:10.1038/426114a


Night club p116

Growing numbers of amateurs are getting serious about astronomy. The professionals applaud their enthusiasm and success in collecting data and building telescopes — as long as they don't start competing with them for funding. Geoff Brumfiel joins the graveyard shift.

doi:10.1038/426116a


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Correspondence

How genius can smooth the road to publication p119

If at first your paper doesn't succeed, try, try — and try to find a brilliant supporter.

Jens Brümmer

doi:10.1038/426119a


How genius can smooth the road to publication p119

John Maddox

doi:10.1038/426119b


Phosphorus: time for us to oust bad spelling p119

Nelson Hairston, Jr

doi:10.1038/426119c


Drinking your health? It's too early to say p119

Roger Corder, Alan Crozier and Paul A. Kroon

doi:10.1038/426119d


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Books and Arts

Web masters p121

Spiders' silky skills hold the key to their evolutionary success.

Fritz Vollrath reviews Spider Webs and Silks: Tracing Evolution from Molecules to Genes to Phenotypes by Catherine L. Craig

doi:10.1038/426121a


From genes to biochemistry p122

Benno Müller-Hill reviews George Beadle, an Uncommon Farmer: The Emergence of Genetics in the 20th Century by Paul Berg and Maxine Singer

doi:10.1038/426122a


A recipe for success? p122

John Mann reviews Organic Syntheses Database

doi:10.1038/426122b


Installation: Making haze p123

Colin Martin

doi:10.1038/426123a


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Concepts

Cancer robustness: Tumour tactics p125

Hiroaki Kitano

doi:10.1038/426125a


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News and Views

Evolutionary biology: Essence of mitochondria p127

For years, a unicellular creature called Giardia has occupied a special place in biology because it was thought to lack mitochondria. But it does have them — though tiny, they pack a surprising anaerobic punch.

Katrin Henze and William Martin

doi:10.1038/426127a


Chemistry: Dendrimers set to self-destruct p128

The versatility of the branched macromolecules known as dendrimers is being exploited in various ways — explosively so, in the context of their application as potential drug-delivery systems.

E. W. Meijer and M. H. P. van Genderen

doi:10.1038/426128a


Virology: Fresh assault on hepatitis C p129

Hepatitis C virus causes severe liver disease. Initial trials of a newly developed agent that prevents the virus reproducing itself look promising. But what are the future prospects for this treatment?

Charles M. Rice

doi:10.1038/nature02105


Materials science: Close-up on cracks p131

How do things break? The fracture of materials is part of our everyday experience, and yet the process is not well understood. A study of crack propagation at microscopic scales shows the devil in the details.

Jay Fineberg

doi:10.1038/426131a


100 and 50 years ago p132

doi:10.1038/426132a


Plant development: An axis of auxin p132

Embryos have two distinct ends, which become apparent early on. Quite how this initial polarity is sustained in plant embryos has been unclear. Step forward the agent provocateur of plant development — auxin.

Stefan Kepinski and Ottoline Leyser

doi:10.1038/426132b


Condensed-matter physics: The quest for imperfection p135

The electrical properties of silver chalcogenides are unusually affected by magnetic fields. A simulation suggests how this might arise from tiny imperfections and could facilitate the design of new materials.

Thomas F. Rosenbaum

doi:10.1038/426135a


News and views in brief p136

doi:10.1038/426136a


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Brief Communications

Radar imaging of the lunar poles p137

Long-wavelength measurements reveal a paucity of ice in the Moon's polar craters.

Bruce A. Campbell, Donald B. Campbell, John F. Chandler, Alice A. Hine, Michael C. Nolan and Phillip J. Perillat

doi:10.1038/426137a


Astrophysics: refreshed shocks from a bold gamma-ray burst p138

Jonathan Granot, Ehud Nakar and Tsvi Piran

doi:10.1038/426138a


Astrophysics (communication arising): A constraint on canonical quantum gravity? p139

Igor G. Mitrofanov

doi:10.1038/426139a


Condensed-matter physics (communication arising): Spurious magnetism in high-Tc superconductor p139

P. K. Mang, S. Larochelle and M. Greven

doi:10.1038/426139b


Condensed-matter physics (communication arising): Spurious magnetism in high-Tc superconductor p140

H. J. Kang, Pengcheng Dai, J. W. Lynn, M. Matsuura, J. R. Thompson, Shou-Cheng Zhang, D. N. Argyriou, Y. Onose and Y. Tokura

doi:10.1038/426140a


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Articles

Hyperelasticity governs dynamic fracture at a critical length scale p141

Markus J. Buehler, Farid F. Abraham and Huajian Gao

doi:10.1038/nature02096

See also: News and Views by Fineberg


Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis p147

Jir caroní Friml, Anne Vieten, Michael Sauer, Dolf Weijers, Heinz Schwarz, Thorsten Hamann, Remko Offringa and Gerd Jürgens

doi:10.1038/nature02085

See also: News and Views by Kepinski & Leyser


Top

Letters to Nature

A common origin for cosmic explosions inferred from calorimetry of GRB030329 p154

E. Berger, S. R. Kulkarni, G. Pooley, D. A. Frail, V. McIntyre, R. M. Wark, R. Sari, A. M. Soderberg, D. W. Fox, S. Yost and P. A. Price

doi:10.1038/nature01998


Evolution of the polarization of the optical afterglow of the bold gamma-ray burst GRB030329 p157

Jochen Greiner, Sylvio Klose, Klaus Reinsch, Hans Martin Schmid, Re'em Sari, Dieter H. Hartmann, Chryssa Kouveliotou, Arne Rau, Eliana Palazzi, Christian Straubmeier, Bringfried Stecklum, Sergej Zharikov, Gaghik Tovmassian, Otto Bärnbantner, Christoph Ries, Emmanuel Jehin, Arne Henden, Anlaug A. Kaas, Tommy Grav, Jens Hjorth, Holger Pedersen, Ralph A. M. J. Wijers, Andreas Kaufer, Hye-Sook Park, Grant Williams and Olaf Reimer

doi:10.1038/nature02077


Experimental observation of symmetry-breaking nonlinear modes in an active ring p159

Sergej O. Demokritov, Alexander A. Serga, Vladislav E. Demidov, Burkard Hillebrands, Michail P. Kostylev and Boris A. Kalinikos

doi:10.1038/nature02042


Non-saturating magnetoresistance in heavily disordered semiconductors p162

M. M. Parish and P. B. Littlewood

doi:10.1038/nature02073

See also: News and Views by Rosenbaum


A polymer/semiconductor write-once read-many-times memory p166

Sven Möller, Craig Perlov, Warren Jackson, Carl Taussig and Stephen R. Forrest

doi:10.1038/nature02070


Rapid body size decline in Alaskan Pleistocene horses before extinction p169

R. Dale Guthrie

doi:10.1038/nature02098


Mitochondrial remnant organelles of Giardia function in iron-sulphur protein maturation p172

Jorge Tovar, Gloria León-Avila, Lidya B Sánchez, Robert Sutak, Jan Tachezy, Mark van der Giezen, Manuel Hernández, Miklós Müller and John M. Lucocq

doi:10.1038/nature01945

See also: News and Views by Henze & Martin


Allele substitution at a flower colour locus produces a pollinator shift in monkeyflowers p176

H. D. Bradshaw, Jr and Douglas W. Schemske

doi:10.1038/nature02106


Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds p178

Takashi Yoshimura, Shinobu Yasuo, Miwa Watanabe, Masayuki Iigo, Takashi Yamamura, Kanjun Hirunagi and Shizufumi Ebihara

doi:10.1038/nature02117


APL regulates vascular tissue identity in Arabidopsis p181

Martin Bonke, Siripong Thitamadee, Ari Pekka Mähönen, Marie-Theres Hauser and Ykä Helariutta

doi:10.1038/nature02100


An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus p186

Daniel Lamarre, Paul C. Anderson, Murray Bailey, Pierre Beaulieu, Gordon Bolger, Pierre Bonneau, Michael Bös, Dale R. Cameron, Mireille Cartier, Michael G. Cordingley, Anne-Marie Faucher, Nathalie Goudreau, Stephen H. Kawai, George Kukolj, Lisette Lagacé, Steven R. LaPlante, Hans Narjes, Marc-André Poupart, Jean Rancourt, Roel E. Sentjens, Roger St George, Bruno Simoneau, Gerhard Steinmann, Diane Thibeault, Youla S. Tsantrizos, Steven M. Weldon, Chan-Loi Yong and Montse Llinàs-Brunet

doi:10.1038/nature02099


CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-bold gamma p190

Stephan Herzig, Susan Hedrick, Ianessa Morantte, Seung-Hoi Koo, Francesco Galimi and Marc Montminy

doi:10.1038/nature02110


A DNA damage checkpoint response in telomere-initiated senescence p194

Fabrizio d'Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas von Zglinicki, Gabriele Saretzki, Nigel P. Carter and Stephen P. Jackson

doi:10.1038/nature02118


DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA p198

Ming Lei, Elaine R. Podell, Peter Baumann and Thomas R. Cech

doi:10.1038/nature02092


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New on the Market

Warming to the task p205

New for PCR, thermocyclers and DNA handling.

doi:10.1038/426205a


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Naturejobs

Prospects

A question of gender p209

Paul Smaglik

doi:10.1038/nj6963-209a


SPECIAL REPORT

Europe attempts to promote women scientists p210

Europe is pushing to get more women scientists into industry and academia, but can the commission legislate for gender equality? Sally Goodman investigates.

Sally Goodman

doi:10.1038/nj6963-210a


The quota conundrum p211

Nicola Nosengo

doi:10.1038/nj6963-211a


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