Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 425, 778-779 (23 October 2003) | doi:10.1038/425778a
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Basic Science Medical Educators
- Texas Tech University Health Sciences Center
- El Paso, Texas, USA
Postdoctoral Fellow - Computational Genomics - Team 78 – Ref: 80464
- Wellcome Trust Sanger Institute
- Hinxton, Cambridgeshire CB10 1, UK
Stem cells: Interactive niches
Ihor R. Lemischka1 & Kateri A. Moore1
Abstract
The microenvironment, or niche, in which stem cells reside controls their renewal and maturation. The niche that regulates blood-forming stem cells in adult animals has eluded researchers — until now.
Cell-fate decisions in the developing embryo are governed by a complex interplay between cell-autonomous signals and stimuli from the surrounding tissue — the microenvironment. Similar processes control the birth and maturation of stem cells that replenish mature cell populations in adults1, 2.
- Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.
Correspondence to: Ihor R. Lemischka1 Email: ilemischka@molbio.princeton.edu
To read this story in full you will need to login or make a payment (see right).
