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Volume 425 Issue 6960, 23 October 2003

Editorial

  • Genetically selected medicine has been much hyped but has significant potential. Regulation and treatment will depend on pharmaceutical companies more readily sharing genetic data.

    Editorial

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  • A United Nations scheme launched last week extends unrestricted access to Nature's content within developing countries.

    Editorial
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News

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News in Brief

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News Feature

  • A new effort to map human genetic variation should provide a shortcut for researchers trying to uncover the roots of disease. Carina Dennis profiles the 'HapMap' project.

    • Carina Dennis
    News Feature
  • Truly 'personalized' medicine remains a distant goal. But researchers are now thinking about how to use genomic data to avoid prescribing drugs that may kill, or won't work. Alison Abbott reports.

    • Alison Abbott
    News Feature
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Correspondence

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Books & Arts

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Lifeline

  • Vera Rubin, senior fellow in the Department of Terrestrial Magnetism, Carnegie Institution of Washington, is wife, parent and astronomer, in that order. She and husband Bob have four PhD offspring: two geologists, an astronomer and a mathematician.

    Lifeline
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News & Views

  • The finished sequence of human chromosome 6 reveals an abundance of biological information previously buried within the draft of the human genome, and illustrates the increasing power of comparative genomics.

    • Jane Grimwood
    • Jeremy Schmutz
    News & Views
  • Astronomers crave a detector sensitive enough to detect a single photon and determine its energy. A new single-pixel device can do this, and could also be built up into a large array suitable for a telescope.

    • Daniel E. Prober
    News & Views
  • The microenvironment, or niche, in which stem cells reside controls their renewal and maturation. The niche that regulates blood-forming stem cells in adult animals has eluded researchers — until now.

    • Ihor R. Lemischka
    • Kateri A. Moore
    News & Views
  • Warm-blooded animals of the same species, living in different climates, have different metabolic rates. In birds, this variation is not only due to physiological adaptation — it is inherent in the animals' genes.

    • Robert W. Furness
    News & Views
  • The genetics of development can often explain the genesis of cancer. This now seems to be true for cancers of the gut, but the patterns of gene expression in these tumours tell a tale with a twist.

    • Matthew P. Scott
    News & Views
  • Recovering the true evolutionary history of any group of organisms has seemed impossible. The availability of large amounts of genomic data promises an era in which the uncertainties are better constrained.

    • Henry Gee
    News & Views
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Brief Communication

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Review Article

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Article

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Letter

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Technology Feature

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Prospects

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Careers and Recruitment

  • Rapidly changing technology and an abundance of DNA sequences are creating more job opportunities in functional genomics — particularly for scientists who have been trained outside traditional biology. Hannah Hoag investigates.

    • Hannah Hoag
    Careers and Recruitment
  • The costs of functional genomics can be prohibitive, and job candidates often lack the skills most researchers desire, but many academic settings are creating training schemes and unique institutes to deal with these barriers. Hannah Hoag reports.

    • Hannah Hoag
    Careers and Recruitment
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