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Editorial

Coping with peer rejection p645

Accounts of rejected Nobel-winning discoveries highlight the conservatism in science. Despite their historical misjudgements, journal editors can help, but above all, visionaries will need sheer persistence.

doi:10.1038/425645a


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News

Health chiefs poised to step up US scrutiny of microbe research p647

Erika Check

doi:10.1038/425647a


Routine tests reveal unknown strains of BSE prions p648

Marika Willerroider

doi:10.1038/425648a


Physician launches public protest over medical Nobel p648

Helen Pearson

doi:10.1038/425648b


Earthquake makes waves for tsunami models p649

David Cyranoski

doi:10.1038/425649a


Bleak forecast for space weather p649

Tony Reichhardt

doi:10.1038/425649b


Congress split over funding for 'safe' nuclear reactor p650

Geoff Brumfiel

doi:10.1038/425650a


Letters reveal scale of German agency's Nazi corruption p650

Quirin Schiermeier

doi:10.1038/425650b


Channel hoppers land chemistry Nobel p651

Jim Giles

doi:10.1038/425651a


Economics prize for duo who resolved random results p651

Philip Ball

doi:10.1038/425651b


News in brief p652

doi:10.1038/425652a


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News Features

Time to choose p655

In some countries, transgenic plants are already a part of mainstream farming. Will the rest of the world soon follow suit?

doi:10.1038/425655a


Damned if they do, damned if they don't... p656

It's crunch time for agribiotech in Britain, as politicians rule on the planting of commercial transgenic crops. The world is watching, says Jim Giles.

doi:10.1038/425656a


GM world view p658

Today, just four countries account for 99% of the world's commercially grown transgenic crops. But that is all changing: policies are being thrashed out, laws drawn up and seeds sown. We present an interactive graphic showing how GM is taking root.

doi:10.1038/425658a


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Correspondence

Effective protection may alter the look of Venice p661

Those seeking to rescue Venice are caught between the devil and the deep-blue sea.

Jean-Daniel Stanley

doi:10.1038/425661a


How do impact factors relate to the real world? p661

Piotr Skórka

doi:10.1038/425661b


Pointless suffering of animals can be avoided p661

Neal D. Barnard

doi:10.1038/425661c


JET at risk if Europe can not afford to pay for ITER p661

A. M. Bradshaw

doi:10.1038/425661d


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Books and Arts

Science exiled p663

How the complexities of science suffer in the arena of public policy.

Paul M. Grant reviews Politicizing Science: The Alchemy of Policymaking

doi:10.1038/425663a


Smashed into orbit p664

Joseph A. Burns reviews The Big Splat, or How Our Moon Came to Be by Dana Mackenzie

doi:10.1038/425664a


In retrospect p665

Paul N. Pearson reviews An Investigation of the Principles of Knowledge and of the Progress of Reason, from Sense to Science and Philosophy by James Hutton

doi:10.1038/425665a


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Concepts

Auxetic materials: Avoiding the shrink p667

Ray H. Baughman

doi:10.1038/425667a


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News and Views

Biogeography: The coelacanth of frogs p669

A frog that lives in the mountains of southern India is a rare breed indeed: it is a new species that merits the establishment of a new family. Moreover, this is a discovery with considerable biogeographical significance.

S. Blair Hedges

doi:10.1038/425669a


Earthquakes: Good tidings p670

Tidal stresses in the Earth's crust don't seem to influence earthquakes. Water wells, on the other hand, seem strangely sensitive to seismic activity. Explanations are now proposed.

Christopher H. Scholz

doi:10.1038/425670a


Proteomics: Where's Waldo in yeast? p671

Research in yeast provides the tools and benchmarks for a wide sweep of biology. The latest results reveal the most complete picture yet of the levels and locations of protein production in the organism.

James A. Wohlschlegel and John R. Yates

doi:10.1038/425671a


Solar physics: Heat exposure p672

The outermost layers of the Sun are hotter than expected. Observation and analysis now confirm that magnetic fields are involved in the heating process, and also signal the existence of a long-sought 'current sheet'.

Robert Rosner

doi:10.1038/425672a


Prion diseases: A nucleic-acid accomplice? p673

Prion proteins that trigger a cascade of protein misfolding in the brain are suspected of being the sole transmissible cause of some brain-destroying diseases. But nucleic acids could be their partner in crime.

Byron Caughey and David A. Kocisko

doi:10.1038/425673a


Materials science: Zero-expansion plan p674

Some materials don't expand or contract as they are heated. A new example is a metallic compound, for which the movement of electrons between atoms is the likely explanation for its 'zero thermal expansion'.

Arthur Sleight

doi:10.1038/425674a


100 and 50 years ago p676

doi:10.1038/425676a


Evolution: Opportunity versus innovation p676

Why have some evolutionary lineages produced many more species than others? As far as one large group of birds is concerned, being in the right place at the right time is a plausible answer.

Paul H. Harvey and Andy Purvis

doi:10.1038/425676b


Astronomy: Faking it p677

Alison Wright

doi:10.1038/425677a


News and views in brief p678

doi:10.1038/425678a


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Brief Communications

Evolution: Single-gene speciation by left–right reversal p679

A land-snail species of polyphyletic origin results from chirality constraints on mating.

Rei Ueshima and Takahiro Asami

doi:10.1038/425679a


Kinetics: Gaussian statistics in granular gases p680

G. W. Baxter and J. S. Olafsen

doi:10.1038/425680a


Corrigendum p680

doi:10.1038/425680b


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Review

Planning for smallpox outbreaks p681

Neil M. Ferguson, Matt J. Keeling, W. John Edmunds, Raymond Gani, Bryan T. Grenfell, Roy M. Anderson and Steve Leach

doi:10.1038/nature02007


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Article

Global analysis of protein localization in budding yeast p686

Won-Ki Huh, James V. Falvo, Luke C. Gerke, Adam S. Carroll, Russell W. Howson, Jonathan S. Weissman and Erin K. O'Shea

doi:10.1038/nature02026

See also: News and Views by Wohlschlegel & Yates


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Letters to Nature

Three-dimensional magnetic field topology in a region of solar coronal heating p692

S. K. Solanki, A. Lagg, J. Woch, N. Krupp and M. Collados

doi:10.1038/nature02035


The speed of information in a 'fast-light' optical medium p695

Michael D. Stenner, Daniel J. Gauthier and Mark A. Neifeld

doi:10.1038/nature02016


Single-electron transistor of a single organic molecule with access to several redox states p698

Sergey Kubatkin, Andrey Danilov, Mattias Hjort, Jérôme Cornil, Jean-Luc Brédas, Nicolai Stuhr-Hansen, Per Hedegård and Thomas Bjørnholm

doi:10.1038/nature02010


Zero thermal expansion in YbGaGe due to an electronic valence transition p702

James R. Salvador, Fu Guo, Tim Hogan and Mercouri G. Kanatzidis

doi:10.1038/nature02011

See also: News and Views by Sleight


Reduction of soil carbon formation by tropospheric ozone under increased carbon dioxide levels p705

Wendy M. Loya, Kurt S. Pregitzer, Noah J. Karberg, John S. King and Christian P. Giardina

doi:10.1038/nature02047


Flying and swimming animals cruise at a Strouhal number tuned for high power efficiency p707

Graham K. Taylor, Robert L. Nudds and Adrian L. R. Thomas

doi:10.1038/nature02000


New frog family from India reveals an ancient biogeographical link with the Seychelles p711

S. D. Biju and Franky Bossuyt

doi:10.1038/nature02019

See also: News and Views by Hedges


Females increase offspring heterozygosity and fitness through extra-pair matings p714

Katharina Foerster, Kaspar Delhey, Arild Johnsen, Jan T. Lifjeld and Bart Kempenaers

doi:10.1038/nature01969


RNA molecules stimulate prion protein conversion p717

Nathan R. Deleault, Ralf W. Lucassen and Surachai Supattapone

doi:10.1038/nature01979


Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice p721

Julie M. Jones, Pinaki Datta, Srinivasa M. Srinivasula, Weizhen Ji, Sanjeev Gupta, ZhiJia Zhang, Erika Davies, György Hajnóczky, Thomas L. Saunders, Margaret L. Van Keuren, Teresa Fernandes-Alnemri, Miriam H. Meisler and Emad S. Alnemri

doi:10.1038/nature02052


Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking p727

Jonathan S. Bogan, Natalie Hendon, Adrienne E. McKee, Tsu-Shuen Tsao and Harvey F. Lodish

doi:10.1038/nature01989


The tobacco aquaporin NtAQP1 is a membrane CO2 pore with physiological functions p734

Norbert Uehlein, Claudio Lovisolo, Franka Siefritz and Ralf Kaldenhoff

doi:10.1038/nature02027


Global analysis of protein expression in yeast p737

Sina Ghaemmaghami, Won-Ki Huh, Kiowa Bower, Russell W. Howson, Archana Belle, Noah Dephoure, Erin K. O'Shea and Jonathan S. Weissman

doi:10.1038/nature02046

See also: News and Views by Wohlschlegel & Yates


Corrigendum: Invariant scaling relations across tree-dominated communities p741

Brian J. Enquist and Karl J. Niklas

doi:10.1038/nature02023


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New on the Market

Tails of discovery p743

A mouse model, high-throughput assays and more for drug research.

doi:10.1038/425743a


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Naturejobs

Prospects

It could be worse... p745

Paul Smaglik

doi:10.1038/nj6959-745a


REGIONS

Singapore: Filling Biopolis p746

Paul Smaglik

doi:10.1038/nj6959-746a


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