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Volume 425 Issue 6958, 9 October 2003

Editorial

  • The director of the US National Institutes of Health has laid out a plan that would align the world's largest biomedical research agency more closely to the future shape of the life sciences. It deserves political support.

    Editorial

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News

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News in Brief

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Correction

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News Feature

  • A new biology journal, positioned to compete with the likes of Nature, Science and Cell, aims to reinvent the economics of high-quality scientific publishing. Declan Butler examines the bottom line.

    • Declan Butler
    News Feature
  • One grain of sand is a solid. But a lot of grains together can behave like a solid or a liquid. By probing this dual personality, physicists hope to understand a host of real-world systems, says Mark Buchanan.

    • Mark Buchanan
    News Feature
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Correspondence

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Books & Arts

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Lifeline

  • Chris Miller is a Howard Hughes Medical Institute investigator and professor of biochemistry at Brandeis University in Waltham, Massachusetts, and works on ion-channel mechanisms.

    Lifeline
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News & Views

  • Mutations in the presenilin protein are associated with Alzheimer's disease. It now seems that mutant presenilin could wreak havoc on neuronal functions by triggering the activation of certain genes.

    • Mark E. Fortini
    News & Views
  • An analysis of astronomical data suggests not only that the Universe is finite, but also that it has a specific, rather rigid topology. If confirmed, this is a major discovery about the nature of the Universe.

    • George F. R. Ellis
    News & Views
  • Different types of neurons are born in a conserved, sequential order during development. The molecular cogs in the clock-like mechanism driving this process are now being revealed.

    • William A. Harris
    News & Views
  • The association between legumes and nitrogen-fixing bacteria requires molecular recognition to allow bacterial entry into root hairs. The discovery of a novel type of plant receptor clarifies how this happens.

    • Martin Parniske
    • J. Allan Downie
    News & Views
  • In collisions between nuclei, a proton or neutron might be knocked out of one nucleus. Now, two-proton knockout has been demonstrated, opening a new route to the creation of neutron-rich systems for study.

    • David Warner
    News & Views
  • Two studies help reveal the dynamics of memory. New memories that weaken during the day can be strengthened by a period of sleep. And when memories are reactivated, they must be re-stored in order to persist.

    • Karim Nader
    News & Views
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Brief Communication

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Review Article

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Article

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Letter

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New on the Market

  • Light, stereo, scanning, transmission and other angles on microscopy.

    New on the Market
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Prospects

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Career View

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