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Nature 425, 351-352 (25 September 2003) | doi:10.1038/425351a

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Immunology: Professional secrets

Craig R. Roy1

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Looking inside the compartments of certain immune cells — professional antigen-presenting cells — has revealed how the immune system can trigger a cell-killing response to extracellular pathogens.

Our immune system provides effective protection against most pathogens. It can mount a highly specific 'adaptive' response that distinguishes between different sorts of pathogen and activates the appropriate mechanisms to eliminate them.

  1. Craig R. Roy is in the Section of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Conneticut 06536, USA.
    Email: craig.roy@yale.edu