Supplementary information

From the following article:

Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins

Eric A. Gaucher, J. Michael Thomson, Michelle F. Burgan & Steven A. Benner

Nature 425, 285-288(18 September 2003)

doi:10.1038/nature01977

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Supplementary Figure: Multiple sequence alignment of the three reconstructed ancestral sequences juxtaposed to EF from modern E. coli. Asterisks, colons, and periods indicate identical, highly conserved, and moderately conserved positions, respectively. Sites are colored according to amino acid side chain physiochemical properties.

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