Table of contents


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Editorials

Science and the war on terror p107

Two years after the attacks on the World Trade Center, the promised reorientation of US national research priorities proceeds without much direction or conviction.

doi:10.1038/425107a


Here, there and everywhere p107

Not before time, there is now a Nature journal devoted to the most diverse branches of the tree of life.

doi:10.1038/425107b


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News

Agony for researchers as mix-up forces retraction of ecstasy study p109

Jonathan Knight

doi:10.1038/425109a


Brain protein project enlists mice in 'dry run' p110

Alison Abbott

doi:10.1038/425110a


US selects regional biodefence hubs p110

Rex Dalton

doi:10.1038/425110b


Analysis pours cold water on flood theory p111

Quirin Schiermeier

doi:10.1038/425111a


Ministers appointed to engineer revival in Iraqi research p111

Geoff Brumfiel

doi:10.1038/425111b


US reflects on flying eye for transgenic crops p112

Jonathan Knight

doi:10.1038/425112a


Global effort to plot climate change p112

Heike Langenberg

doi:10.1038/425112b


Young guns shoot to the top in China's research revolution p113

David Cyranoski

doi:10.1038/425113a


Esoteric theorist lands starring role in Senate hearing p113

Geoff Brumfiel

doi:10.1038/425113b


News in brief p114

doi:10.1038/425114a


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News Features

Science and law: Biotechnology at the bar p116

Science is moving too fast for the legal system to keep up. But lawyers and scientists have a solution — a body that would help courts tackle cases involving the latest research. Nicola Nosengo investigates.

doi:10.1038/425116a


Drug research: The ups and downs of lithium p118

Lithium has been used to treat manic depression for decades, and may help combat other brain disorders. So how come no one knows for sure why it works? Helen R. Pilcher reports.

doi:10.1038/425118a


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Correspondence

Science and ethics must not be separated p121

The progress of research must be kept free from religious and political intervention.

Paul Copland

doi:10.1038/425121a


Safe home planned for Iowa herbarium p121

Jack Lilien

doi:10.1038/425121b


Computer's ability to verify proof is an illusion p121

Derek Partridge

doi:10.1038/425121c


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Commentary

An ethical dilemma p123

The rise and fall of UmanGenomics — the model biotech company?

doi:10.1038/425123a


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Books and Arts

Net losses p125

Overfishing in the north Atlantic Ocean has left fish stocks in peril.

John Shepherd reviews In a Perfect Ocean by Daniel Pauly and Jay Maclean

doi:10.1038/425125a


More on fisheries p126

doi:10.1038/425126a


New in paperback p126

doi:10.1038/425126b


The proof of the packing p126

Neil Sloane reviews Kepler's Conjecture: How Some of the Greatest Minds in History Helped Solve One of the Oldest Math Problems in the World by George G. Szpiro

doi:10.1038/425126c


The rise and fall of the Universe p127

Peter Coles reviews Alpha and Omega: The Search for the Beginning and the End of the Universe by Charles Seife

doi:10.1038/425127a


Science in culture p128

Martin Kemp reviews

doi:10.1038/425128a


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Lifelines

Yvon Le Maho: How animals work p129

Yvon Le Maho studies how animals adapt to the environment, and is especially fond of penguins. He is director of the CNRS Centre d'Ecologie et Physiologie Energétiques in Strasbourg, France.

doi:10.1038/425129a


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News and Views

Planetary science: Spin control for asteroids p131

Random collisions between asteroids would seem to cause their spin axes to be tilted in all directions. Surprisingly, the gentle recoil force of thermal re-radiation may bring their spin axes into alignment.

Richard P. Binzel

doi:10.1038/425131a


Ageing: A toast to long life p132

Reducing food intake increases lifespan in many species. A small molecule that occurs naturally in plants seems to mimic the beneficial effects of caloric restriction and extend longevity in yeast.

Toren Finkel

doi:10.1038/425132a


Condensed-matter physics: Vortices and hearts p133

A single vortex of flux, formed inside a superconducting Josephson junction, has been detected undergoing quantum tunnelling — a feature that could be developed into a quantum bit.

John Clarke

doi:10.1038/425133a


Behavioural ecology: Father knows best p136

When females mate with several males, paternity may be uncertain. But male savannah baboons are seldom confused: when intervening in fights between youngsters, they generally support their own offspring.

Paul W. Sherman and Bryan D. Neff

doi:10.1038/425136a


Cosmochemistry: Inside the cosmic blender p137

The Solar System has a largely uniform isotopic composition but with tantalizing small variations. Geochemists are trying to ascertain the mechanisms and types of stars that produced this state of affairs.

Alex N. Halliday

doi:10.1038/425137a


Cardiovascular biology: Signalling silenced p139

The mechanism by which the TIMP-2 protein inhibits blood-vessel formation has been uncovered — and it is not as expected. The finding has implications for treating a cancer by cutting off its blood supply.

Edward M. Conway and Peter Carmeliet

doi:10.1038/425139a


Biophysics: Take the intracellular train p140

Magdalena Helmer

doi:10.1038/425140a


Clarification p141

doi:10.1038/425141a


100 and 50 years ago p141

doi:10.1038/425141b


Obituary: Thomas Risley Odhiambo (1931–2003) p142

Rachel Galun and Onesmo K. ole-MoiYoi

doi:10.1038/425142a


News and views in brief p143

doi:10.1038/425143a


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Brief Communications

Photomechanics: Directed bending of a polymer film by light p145

Miniaturizing a simple photomechanical system could expand its range of applications.

Yanlei Yu, Makoto Nakano and Tomiki Ikeda

doi:10.1038/425145a


Reproduction: Widespread cloning in echinoderm larvae p146

Alexandra A. Eaves and A. Richard Palmer

doi:10.1038/425146a


Top

Article

The vector alignments of asteroid spins by thermal torques p147

David Vokrouhlický, David Nesvorný and William F. Bottke

doi:10.1038/nature01948

See also: News and Views by Binzel


Top

Letters to Nature

Efficient mixing of the solar nebula from uniform Mo isotopic composition of meteorites p152

Harry Becker and Richard J. Walker

doi:10.1038/nature01975

See also: News and Views by Halliday


Quantum dynamics of a single vortex p155

A. Wallraff, A. Lukashenko, J. Lisenfeld, A. Kemp, M. V. Fistul, Y. Koval and A. V. Ustinov

doi:10.1038/nature01826

See also: News and Views by Clarke


Efficient bulk heterojunction photovoltaic cells using small-molecular-weight organic thin films p158

Peter Peumans, Soichi Uchida and Stephen R. Forrest

doi:10.1038/nature01949


Lubrication by charged polymers p163

Uri Raviv, Suzanne Giasson, Nir Kampf, Jean-François Gohy, Robert Jérôme and Jacob Klein

doi:10.1038/nature01970


No upward trends in the occurrence of extreme floods in central Europe p166

Manfred Mudelsee, Michael Börngen, Gerd Tetzlaff and Uwe Grünewald

doi:10.1038/nature01928


Radiometric dating of the Siloam Tunnel, Jerusalem p169

Amos Frumkin, Aryeh Shimron and Jeff Rosenbaum

doi:10.1038/nature01875


Extreme reversed sexual size dimorphism in the extinct New Zealand moa Dinornis p172

Michael Bunce, Trevor H. Worthy, Tom Ford, Will Hoppitt, Eske Willerslev, Alexei Drummond and Alan Cooper

doi:10.1038/nature01871


Nuclear DNA sequences detect species limits in ancient moa p175

L. Huynen, C. D. Millar, R. P. Scofield and D. M. Lambert

doi:10.1038/nature01838


True paternal care in a multi-male primate society p179

Jason C. Buchan, Susan C. Alberts, Joan B. Silk and Jeanne Altmann

doi:10.1038/nature01866

See also: News and Views by Sherman & Neff


Motion-induced spatial conflict p181

Derek H. Arnold and Alan Johnston

doi:10.1038/nature01955


Cellular networks underlying human spatial navigation p184

Arne D. Ekstrom, Michael J. Kahana, Jeremy B. Caplan, Tony A. Fields, Eve A. Isham, Ehren L. Newman and Itzhak Fried

doi:10.1038/nature01964


Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation p188

Philipp Stelter and Helle D. Ulrich

doi:10.1038/nature01965


Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan p191

Konrad T. Howitz, Kevin J. Bitterman, Haim Y. Cohen, Dudley W. Lamming, Siva Lavu, Jason G. Wood, Robert E. Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang, Brandy Scherer and David A. Sinclair

doi:10.1038/nature01960

See also: News and Views by Finkel


A cell surface receptor mediates extracellular Ca2+ sensing in guard cells p196

Shengcheng Han, Ruhang Tang, Lisa K. Anderson, Todd E. Woerner and Zhen-Ming Pei

doi:10.1038/nature01932


Structural basis for modulation and agonist specificity of HCN pacemaker channels p200

William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson and Eric Gouaux

doi:10.1038/nature01922


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New on the Market

Patents, programs and proteins p206

Personalized search, personalized plasmids.

doi:10.1038/425206a


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Technology Features

Bioinformatics: Programmed for success p209

Advanced software and services aimed at the non-bioinformatician are making it easier to ride the tidal-wave of genomics and proteomics data. Steve Buckingham reports.

Steve Buckingham

doi:10.1038/425209a


Finding your way p209

Steve Buckingham

doi:10.1038/425209b


Seeing is believing p211

Steve Buckingham

doi:10.1038/425211a


Genomic mergers p213

Steve Buckingham

doi:10.1038/425213a


Table of suppliers p216

doi:10.1038/425216a


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Naturejobs

Prospects

Fact or fiction? p219

Paul Smaglik

doi:10.1038/nj6954-219a


SPECIAL REPORT

Making the move from physics to finance p220

Each year, some scientists switch careers to become consultants. But can they weather the current economic storm? Tobias Kramer and Amy Wilson investigate.

Tobias Kramer and Amy Wilson

doi:10.1038/nj6954-220a


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