FIGURE 2. Place-responsive cells.

a, Firing-rate map of a right hippocampal cell showing significant place selectivity. Letters (S_A,S_B,S_C) indicate shop locations, white boxes indicate non-target buildings, grey boxes indicate unoccupied areas, red lines indicate the subject's trajectory, and black squares indicate regions of significantly high firing rate (all examples, P < 0.01; see Methods). b, Place-responsive cells were clustered in the hippocampus (H) compared with amygdala (A), parahippocampal region (PR) and frontal lobes (FR). c, Regions of high firing included high numbers of traversals in different directions. The distribution of firing-rate differences across these traversals was centred on zero and normal. d, Firing-rate map of a right hippocampal cell showing significant place selectivity when searching for shop S_C, but no such specificity when searching for other goals (e, areas with <2 traversals were excluded). f, This cell similarly showed no effect of viewing specific targets (P indicates viewing passengers; N indicates a control background view).