Figures and Tables

From the following article:

Structural basis for modulation and agonist specificity of HCN pacemaker channels

William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson and Eric Gouaux

Nature 425, 200-205(11 September 2003)

doi:10.1038/nature01922

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

HCN2 channel topology and alignment with related channels.

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Figure 2

Structure of the mouse HCN2 C-linker and CNBD construct bound to cAMP.

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Figure 3

cAMP and cGMP bind to the same site with different stereochemistry.

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Figure 4

C-linker interactions and cyclic nucleotide-dependent tetramer formation.

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Table 1

Crystallographic refinement statistics

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