Table of contents
Volume 424 Number 6948 pp473-597
Editorials
Diversity in food technology p473
A scientific review, farm-scale trials and extensive public consultations on genetically modified crops should pave the way for greater benefits and choice for consumers — provided that the organic movement abandons self-damaging dogmas.
doi:10.1038/424473a
Dangers of privatization p473
The Bush administration's drive to contract out services is a threat to science.
doi:10.1038/424473b
News
Expert panel retreats from major restructuring in blueprint for NIH p475
Erika Check
doi:10.1038/424475a
Strategy for climate research gets cool response p475
Geoff Brumfiel
doi:10.1038/424475b
Maize map sees geneticists split over choice of direction p476
Carina Dennis
doi:10.1038/424476a
Russian scientists face long fight for justice p477
Bryon MacWilliams
doi:10.1038/424477a
Anger grows over plan to uproot Indian crop institute p477
K. S. Jayaraman
doi:10.1038/424477b
Satellites aim to shake up quake predictions p478
Tony Reichhardt
doi:10.1038/424478a
US researchers fear job losses from privatization drive p478
Rex Dalton
doi:10.1038/424478b
Whale genetics study leaves conservationists all at sea p479
Tom Clarke and Jonathan Knight
doi:10.1038/424479a
US bombshell hits revamp of Russian weapons centres p479
Geoff Brumfiel
doi:10.1038/424479b
News Features
Palaeobiology: Setting the record straight p482
By analysing masses of data from fossils throughout the world, a group of palaeontologists hopes to address the big questions about the history of life on Earth. Quirin Schiermeier logs on to the Paleobiology Database.
doi:10.1038/424482a
Computing: Quantum bits and silicon chips p484
Quantum computers offer a new kind of processing power. Silicon chips are easy to manufacture. Can the advantages of the two approaches be combined? Jenny Hogan reports.
doi:10.1038/424484a
Correspondence
Impact factors reward and promote excellence p487
The system is unkind but effective. Others would do less good for developing countries.
Adam 
omnicki
doi:10.1038/424487a
Impact factors: letting everyone have their say p487
Matthew Cobb
doi:10.1038/424487b
Books and Arts
Beware of false profits p489
Academics must consider the true cost of dealings with the marketplace.
Jeremy Gunawardena reviews Universities in the Marketplace: The Commercialization of Higher Education by Derek Bok
doi:10.1038/424489a
A child in time p490
Paul Bahn reviews Portrait of the Artist as a Child: The Gravettian Human Skeleton from the Abrigo do Lagar Velho and its Archeological Context
doi:10.1038/424490a
Nature's magic bullets p491
Stewart T. Cole reviews Antibiotics: Actions, Origins, Resistance by Christopher Walsh
doi:10.1038/424491a
Online database: Island investigations p491
Alison Abbott
doi:10.1038/424491b
News and Views
Radiation: A dose of the bomb p495
Measurements of high-energy neutron exposure in Hiroshima validate estimates of the amount of radiation that survivors of the atom bomb received. Can we now predict the risks of radiation more reliably?
Mark P. Little
doi:10.1038/424495a
Global change: South dials north p496
Climate is greatly influenced by ocean circulation in the North Atlantic. But warming episodes, as glacial conditions turned into interglacials, may have been triggered by events far to the south.
Thomas F. Stocker
doi:10.1038/424496a
Developmental biology: How to turn inside out p499
The discovery that a molecular motor of the kinesin family is involved in turning a multicellular green alga inside out might have implications for similar events in animal development.
Rüdiger Schmitt and Manfred Sumper
doi:10.1038/424499a
Materials science: The road to diamond wafers p500
Diamond could rival silicon as the material of choice for the electronics industry, but has been held back by the difficulty of growing large enough wafers. This problem may now be solved.
S. T. Lee and Y. Lifshitz
doi:10.1038/424500a
Theoretical biology: Safeguards and spurs p501
Biological traits are buffered against genetic and environmental upset by a process called canalization. New work suggests this may be a general feature of regulatory gene networks, selected to survive gene loss.
Stephen C. Stearns
doi:10.1038/424501a
Neurobiology: Motor proteins branch out p503
Amanda Tromans
doi:10.1038/424503a
Condensed-matter physics: Singular behaviour p504
Quantum fluctuations at absolute zero may push a system into a different phase or state. The 'quantum critical point' at which this happens in certain materials has now been probed in greater detail.
Zachary Fisk
doi:10.1038/424504a
Cell biology: Moving inside membranes p505
The mechanism that inserts proteins into the membranes of cellular organelles was thought to be well understood. But studies in yeast reveal that this process is sometimes more complicated than had been suspected.
Katsuyoshi Mihara
doi:10.1038/424505a
100 and 50 years ago p505
doi:10.1038/424505b
News and views in brief p507
doi:10.1038/424507a
Brief Communications
Biomechanics: Froghopper insects leap to new heights p509
An innovative leaping action propels these bugs to the top of the insect athletic league.
Malcolm Burrows
doi:10.1038/424509a
First paragraph | Full Text | PDF (92K) | Supplementary information
Fibre optics: Surgery by sunlight on live animals p510
Jeffrey M. Gordon, Daniel Feuermann, Mahmoud Huleihil, Solly Mizrahi and Ruthy Shaco-Levy
doi:10.1038/424510a
Erratum: Vortex rings in a constant electric field p510
doi:10.1038/424510b
Articles
Transformation and control of ultra-short pulses in dispersion-engineered photonic crystal fibres p511
W. H. Reeves, D. V. Skryabin, F. Biancalana, J. C. Knight, P. St. J. Russell, F. G. Omenetto, A. Efimov and A. J. Taylor
doi:10.1038/nature01798
Abstract | Full Text | PDF (427K)
Integration of interferon-
/
signalling to p53 responses in tumour suppression and antiviral defence p516
Akinori Takaoka, Sumio Hayakawa, Hideyuki Yanai, Dagmar Stoiber, Hideo Negishi, Hideaki Kikuchi, Shigeru Sasaki, Kohzoh Imai, Tsukasa Shibue, Kenya Honda and Tadatsugu Taniguchi
doi:10.1038/nature01850
Abstract | Full Text | PDF (495K) | Supplementary information
Letters to Nature
The break-up of heavy electrons at a quantum critical point p524
J. Custers, P. Gegenwart, H. Wilhelm, K. Neumaier, Y. Tokiwa, O. Trovarelli, C. Geibel, F. Steglich, C. Pépin and P. Coleman
doi:10.1038/nature01774
First paragraph | Full Text | PDF (441K)
See also: News and Views by Fisk
Superconductivity phase diagram of NaxCoO2
1.3H2O p527
R. E. Schaak, T. Klimczuk, M. L. Foo and R. J. Cava
doi:10.1038/nature01877
First paragraph | Full Text | PDF (303K)
A recyclable catalyst that precipitates at the end of the reaction p530
Vladimir K. Dioumaev and R. Morris Bullock
First paragraph | Full Text | PDF (177K) | Supplementary information
Southern Ocean origin for the resumption of Atlantic thermohaline circulation during deglaciation p532
Gregor Knorr and Gerrit Lohmann
doi:10.1038/nature01855
First paragraph | Full Text | PDF (530K) | Supplementary information
See also: News and Views by Stocker
Possible thermal and chemical stabilization of body-centred-cubic iron in the Earth's core p536
Lidunka Vo
adlo,
Dario Alfè,
M. J. Gillan,
I. G. Wood,
J. P. Brodholt
and
G. David Price
doi:10.1038/nature01829
First paragraph | Full Text | PDF (454K)
Measuring fast neutrons in Hiroshima at distances relevant to atomic-bomb survivors p539
T. Straume, G. Rugel, A. A. Marchetti, W. Rühm, G. Korschinek, J. E. McAninch, K. Carroll, S. Egbert, T. Faestermann, K. Knie, R. Martinelli, A. Wallner and C. Wallner
doi:10.1038/nature01815
First paragraph | Full Text | PDF (175K)
See also: News and Views by Little
Niche lability in the evolution of a Caribbean lizard community p542
Jonathan B. Losos, Manuel Leal, Richard E. Glor, Kevin de Queiroz, Paul E. Hertz, Lourdes Rodríguez Schettino, Ada Chamizo Lara, Todd R. Jackman and Allan Larson
doi:10.1038/nature01814
First paragraph | Full Text | PDF (179K) | Supplementary information
Constrained circulation at Endeavour ridge facilitates colonization by vent larvae p545
Richard E. Thomson, Steven F. Mihály, Alexander B. Rabinovich, Russell E. McDuff, Scott R. Veirs and Frederick R. Stahr
doi:10.1038/nature01824
First paragraph | Full Text | PDF (425K)
Evolutionary capacitance as a general feature of complex gene networks p549
Aviv Bergman and Mark L. Siegal
doi:10.1038/nature01765
First paragraph | Full Text | PDF (150K) | Supplementary information
See also: News and Views by Stearns
Organization of cell assemblies in the hippocampus p552
Kenneth D. Harris, Jozsef Csicsvari, Hajime Hirase, George Dragoi and György Buzsáki
doi:10.1038/nature01834
First paragraph | Full Text | PDF (621K) | Supplementary information
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration p556
Yih-Cherng Liou, Anyang Sun, Akihide Ryo, Xiao Zhen Zhou, Zhao-Xue Yu, Han-Kuei Huang, Takafumi Uchida, Roderick Bronson, Guoying Bing, Xiaojiang Li, Tony Hunter and Kun Ping Lu
doi:10.1038/nature01832
First paragraph | Full Text | PDF (539K) | Supplementary information
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression p561
Carola A. Neumann, Daniela S. Krause, Christopher V. Carman, Shampa Das, Devendra P. Dubey, Jennifer L. Abraham, Roderick T. Bronson, Yuko Fujiwara, Stuart H. Orkin and Richard A. Van Etten
doi:10.1038/nature01819
First paragraph | Full Text | PDF (418K) | Supplementary information
Machinery for protein sorting and assembly in the mitochondrial outer membrane p565
Nils Wiedemann, Vera Kozjak, Agnieszka Chacinska, Birgit Schönfisch, Sabine Rospert, Michael T. Ryan, Nikolaus Pfanner and Chris Meisinger
doi:10.1038/nature01753
First paragraph | Full Text | PDF (845K)
See also: News and Views by Mihara
Dimers of the N-terminal domain of phytochrome B are functional in the nucleus p571
Tomonao Matsushita, Nobuyoshi Mochizuki and Akira Nagatani
doi:10.1038/nature01837
First paragraph | Full Text | PDF (428K) | Supplementary information
Processivity of the single-headed kinesin KIF1A through biased binding to tubulin p574
Yasushi Okada, Hideo Higuchi and Nobutaka Hirokawa
doi:10.1038/nature01804
First paragraph | Full Text | PDF (423K) | Supplementary information
New on the Market
The latest for the lab p578
Murine accomodation, proteomics and FDA compliance.
doi:10.1038/424578a
Technology Features
proteomics technologies: Probing the proteome p581
The completion of the human genome sequence, coupled with analytical techniques such as mass spectrometry, has fuelled interest in proteomics. Diane Gershon reports.
Diane Gershon
doi:10.1038/424581a
Mass spectrometry goes mainstream p581
Diane Gershon
doi:10.1038/424581b
Look, no hands p583
Diane Gershon
doi:10.1038/424583a
When the chips are down p585
Diane Gershon
doi:10.1038/424585a
table of suppliers p589
doi:10.1038/424589a
Naturejobs
ProspectsRedressing the balance p593
Paul Smaglik
doi:10.1038/nj6948-593a
CAREERS AND RECRUITMENT
Life beyond synthesis p594
Medicinal chemists have skills that are eagerly snapped up by industry, and an increase in training options is making it easier to gain the necessary experience. Eugene Russo reports.
Eugene Russo
doi:10.1038/nj6948-594a
Success in an uneven market p597
Medicinal chemists are in demand more than ever before — but the vagaries of the drug-discovery market and a sluggish economy have dampened prospects temporarily, says Eugene Russo.
Eugene Russo
doi:10.1038/nj6948-597a
