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Nature 424, 505-506 (31 July 2003) | doi:10.1038/424505a

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Cell biology: Moving inside membranes

Katsuyoshi Mihara1

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The mechanism that inserts proteins into the membranes of cellular organelles was thought to be well understood. But studies in yeast reveal that this process is sometimes more complicated than had been suspected.

Rather like the organs of the human body, the 'organelles' of plant, animal and yeast cells are specialized compartments that fulfil specific functions. Each organelle is bounded by a lipid membrane, which contains 'translocase complexes' that ferry proteins from outside the compartment to the inside.

  1. Department of Molecular Biology, Graduate School of Medical Science, Kyushu University, 812-8582 Fukuoka, Japan.
    Email: mihara@cell.med.kyushu-u.ac.jp