Table of contents
Volume 424 Number 6947 pp355-472
Editorials
A calm view of video violence p355
Studies of violence in the media and its effects on people are clouded by overheated rhetoric and exaggerated claims. More clarity is needed, both in the science and in the way it is discussed.
doi:10.1038/424355a
The grand challenges facing physics p355
It would be easy to delay the prioritization of major new projects at US physics laboratories, but it needs to be done.
doi:10.1038/424355b
News
Physics poised for sizeable gains in energy department's wish-list p357
Geoff Brumfiel
doi:10.1038/424357a
US observation initiative calls for fresh view of Earth p357
Tony Reichhardt
doi:10.1038/424357b
UK experts map out route to licensing transgenic crops p358
Jim Giles
doi:10.1038/424358a
Dispute over data privacy halts cancer study p359
David Cyranoski
doi:10.1038/424359a
African project seeks model solution to water shortage p359
Quirin Schiermeier
doi:10.1038/424359b
Brain region linked to post-terror stress p360
David Cyranoski
doi:10.1038/424360a
Museum trustees quit after row over sale of artefacts p360
Rex Dalton
doi:10.1038/424360b
HIV drug resistance triggers strategic switch p361
Erika Check
doi:10.1038/424361a
US budgets for physical endeavour p361
Geoff Brumfiel
doi:10.1038/424361b
News Features
Developmental biology: Synthetic sex cells p364
Some pioneering biologists are trying to grow eggs and sperm in the lab. In doing so, they're entering a technical and ethical minefield. Carina Dennis reports.
doi:10.1038/424364a
Video violence: Playing with fire? p367
The latest computer games involve pretty gruesome scenes — severed limbs and drive-by shootings are standard fare. But opinion is divided on whether such games spark real-life violence. Tony Reichhardt investigates.
doi:10.1038/424367a
Correspondence
Military-funded research is not unethical p369
The key is to ensure that it is the military rather than the scientists who are regulated.
Daniel S. Rizzuto, Boris Breznen and Bradley Greger
doi:10.1038/424369a
Military: brain machine could benefit millions p369
Alan Rudolph
doi:10.1038/424369b
Authorities should note sponsorship–results link p369
Leoluca Criscione
doi:10.1038/424369c
Books and Arts
Uncertainty rules p371
Neuroeconomics seeks to move brain studies beyond the fixed reflex.
P. Read Montague reviews Decisions, Uncertainty, and the Brain: The Science of Neuroeconomics by Paul W. Glimcher
doi:10.1038/424371a
Beauty and the bees p372
Thomas D. Seeley reviews Form and Function in the Honey Bee by Lesley Goodman
doi:10.1038/424372a
Universal support p373
Sean Carroll reviews Echo of the Big Bang by Michael Lemonick
doi:10.1038/424373a
Vesalius's vessels p373
Mary Purton
doi:10.1038/424373b
Concepts
Race: A genetic melting-pot p374
Marcus W. Feldman, Richard C. Lewontin and Mary-Claire King
doi:10.1038/424374a
News and Views
Developmental biology: A tale of tails p375
Developing organisms still hold many surprises for biologists. For instance, an entirely new 'organizer' — a clump of cells that tells other cells what to do — has been discovered at a very early stage of zebrafish development.
Christof Niehrs
doi:10.1038/424375a
Particle physics: Strange days p376
Three new subatomic particles have been found, and all survive for an unusually long time before they decay. Physicists now face the challenge of explaining this within the framework of the existing theory.
Frank Close
doi:10.1038/424376a
Neurobiology: Caught in the act p377
Researchers may have seen the signature of a memory in the making. In monkeys that learnt to associate two stimuli, single neurons changed their responses before, during or after learning became evident.
Yadin Dudai
doi:10.1038/424377a
Materials science: On the straight and narrow p378
Nanoscale chemical patterns written on a substrate can direct the self-assembly of polymer overlayers with remarkable precision. These polymer films, in turn, can be used as templates for nanofabrication.
Richard A. Register
doi:10.1038/424378a
Developmental biology: Boundary lines p379
Embryonic development is a complicated business, as a recent meeting bore witness. The signals generated at the boundaries between compartments were a key topic of discussion.
Seth S. Blair
doi:10.1038/424379a
Neurobiology: A new way to network p381
Guidance molecules called semaphorins ensure that nerve cells grow in the correct direction during development. It now appears that one semaphorin interacts with integrin proteins to produce another effect.
Patrick Mehlen
doi:10.1038/424381a
100 and 50 years ago p381
doi:10.1038/424381b
Astronomy: An early stellar nursery p382
Searching for distant objects in our Universe is equivalent to looking back in time, to the early origins of stars and galaxies. The most distant object known shows the earliest evidence of star formation.
Philip Solomon
doi:10.1038/424382a
Obituary: Ira Herskowitz (1946–2003) p384
Alexander Johnson and Mark Ptashne
doi:10.1038/424384a
News and views in brief p385
doi:10.1038/424385a
Brief Communications
Insect behaviour: Reversal of sex roles in nuptial feeding p387
Female Zeus bugs subvert the traditional notion that amorous gifts are a male preserve.
Göran Arnqvist, Therésa M. Jones and Mark A. Elgar
doi:10.1038/424387a
First paragraph | Full Text | PDF (121K)
Psychophysics: Bees trade off foraging speed for accuracy p388
Lars Chittka, Adrian G. Dyer, Fiola Bock and Anna Dornhaus
doi:10.1038/424388a
First paragraph | Full Text | PDF (83K)
Endocrinology: Bone adaptation requires oestrogen receptor-
p389
Karla Lee, Helen Jessop, Rosemary Suswillo, Gul Zaman and Lance Lanyon
doi:10.1038/424389a
First paragraph | Full Text | PDF (108K)
Metallurgy (communication arising): Stainless-steel corrosion and MnS inclusions p389
Q. Meng, G. S. Frankel, H. O. Colijn and S. H. Goss
doi:10.1038/424389b
First paragraph | Full Text | PDF (108K)
Metallurgy (communication arising): Stainless-steel corrosion and MnS inclusions p390
Mary P. Ryan, David E. Williams, Richard J. Chater, Bernie M. Hutton and David S. McPhail
doi:10.1038/424390a
Articles
Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function p391
Guido Serini, Donatella Valdembri, Sara Zanivan, Giulia Morterra, Constanze Burkhardt, Francesca Caccavari, Luca Zammataro, Luca Primo, Luca Tamagnone, Malcolm Logan, Marc Tessier-Lavigne, Masahiko Taniguchi, Andreas W. Püschel and Federico Bussolino
doi:10.1038/nature01784
Abstract | Full Text | PDF (800K) | Supplementary information
Semaphorin 7A promotes axon outgrowth through integrins and MAPKs p398
R. Jeroen Pasterkamp, Jacques J. Peschon, Melanie K. Spriggs and Alex L. Kolodkin
doi:10.1038/nature01790
Abstract | Full Text | PDF (525K) | Supplementary information
See also: News and Views by Mehlen
Letters to Nature
Molecular gas in the host galaxy of a quasar at redshift z = 6.42 p406
Fabian Walter, Frank Bertoldi, Chris Carilli, Pierre Cox, K. Y. Lo, Roberto Neri, Xiaohui Fan, Alain Omont, Michael A. Strauss and Karl M. Menten
doi:10.1038/nature01821
First paragraph | Full Text | PDF (219K)
See also: News and Views by Solomon
Rotational actuators based on carbon nanotubes p408
A. M. Fennimore, T. D. Yuzvinsky, Wei-Qiang Han, M. S. Fuhrer, J. Cumings and A. Zettl
doi:10.1038/nature01823
First paragraph | Full Text | PDF (227K) | Supplementary information
Epitaxial self-assembly of block copolymers on lithographically defined nanopatterned substrates p411
Sang Ouk Kim, Harun H. Solak, Mark P. Stoykovich, Nicola J. Ferrier, Juan J. de Pablo and Paul F. Nealey
doi:10.1038/nature01775
First paragraph | Full Text | PDF (461K)
See also: News and Views by Register
Carbon solubility in olivine and the mode of carbon storage in the Earth's mantle p414
Hans Keppler, Michael Wiedenbeck and Svyatoslav S. Shcheka
doi:10.1038/nature01828
First paragraph | Full Text | PDF (154K) | Supplementary information
Reflection signature of seismic and aseismic slip on the northern Cascadia subduction interface p416
Mladen R. Nedimovi
,
Roy D. Hyndman,
Kumar Ramachandran
and
George D. Spence
doi:10.1038/nature01840
First paragraph | Full Text | PDF (1,232K)
Catastrophic extinctions follow deforestation in Singapore p420
Barry W. Brook, Navjot S. Sodhi and Peter K. L. Ng
doi:10.1038/nature01795
First paragraph | Full Text | PDF (177K) | Supplementary information
Productivity–biodiversity relationships depend on the history of community assembly p423
Tadashi Fukami and Peter J. Morin
doi:10.1038/nature01785
First paragraph | Full Text | PDF (200K) | Supplementary information
The role of neuronal identity in synaptic competition p426
Narayanan Kasthuri and Jeff W. Lichtman
doi:10.1038/nature01836
First paragraph | Full Text | PDF (474K) | Supplementary information
Genetic evidence that relative synaptic efficacy biases the outcome of synaptic competition p430
Mario Buffelli, Robert W. Burgess, Guoping Feng, Corrinne G. Lobe, Jeff W. Lichtman and Joshua R. Sanes
doi:10.1038/nature01844
First paragraph | Full Text | PDF (535K)
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels p434
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets and Bernd Nilius
doi:10.1038/nature01807
First paragraph | Full Text | PDF (546K)
The expression domain of PHANTASTICA determines leaflet placement in compound leaves p438
Minsung Kim, Sheila McCormick, Marja Timmermans and Neelima Sinha
doi:10.1038/nature01820
First paragraph | Full Text | PDF (696K) | Supplementary information
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5 p443
Vidu Garg, Irfan S. Kathiriya, Robert Barnes, Marie K. Schluterman, Isabelle N. King, Cheryl A. Butler, Caryn R. Rothrock, Reenu S. Eapen, Kayoko Hirayama-Yamada, Kunitaka Joo, Rumiko Matsuoka, Jonathan C. Cohen and Deepak Srivastava
doi:10.1038/nature01827
First paragraph | Full Text | PDF (394K) | Supplementary information
The molecular nature of the zebrafish tail organizer p448
Antoine Agathon, Christine Thisse and Bernard Thisse
doi:10.1038/nature01822
First paragraph | Full Text | PDF (377K) | Supplementary information
See also: News and Views by Niehrs
WAVE2 is required for directed cell migration and cardiovascular development p452
Daisuke Yamazaki, Shiro Suetsugu, Hiroaki Miki, Yuki Kataoka, Shin-Ichi Nishikawa, Takashi Fujiwara, Nobuaki Yoshida and Tadaomi Takenawa
doi:10.1038/nature01770
First paragraph | Full Text | PDF (516K) | Supplementary information
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus p456
Xin Wang, Shu-Mei Huong, Marie L. Chiu, Nancy Raab-Traub and Eng-Shang Huang
doi:10.1038/nature01818
First paragraph | Full Text | PDF (641K)
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo p461
Hironori Katoh and Manabu Negishi
doi:10.1038/nature01817
First paragraph | Full Text | PDF (347K) | Supplementary information
Crystal structure of human cytochrome P450 2C9 with bound warfarin p464
Pamela A. Williams,
Jose Cosme,
Alison Ward,
Hayley C. Angove,
Dijana Matak Vinkovi
and
Harren Jhoti
doi:10.1038/nature01862
First paragraph | Full Text | PDF (462K) | Supplementary information
New on the Market
Gene expression, amplification p469
PCR, thermocyclers and some more software that works with Mac OS X.
doi:10.1038/424469a
Naturejobs
ProspectsA team effort p471
Paul Smaglik
doi:10.1038/nj6947-471a
MOVERS
Movers p472
doi:10.1038/nj6947-472a
