Table of contents
Volume 424 Number 6945 pp113-235
Editorial
We have been warned p113
The world is celebrating the news that the SARS outbreak now seems to be contained. But the epidemic has revealed gaps in our defences against emerging viral diseases and the ever-looming threat of a flu pandemic.
doi:10.1038/424113a
News
Science shunted to the sidelines as EU sets out its space agenda p115
Declan Butler
doi:10.1038/424115a
Pest resistance feared as farmers flout rules p116
Tom Clarke
doi:10.1038/424116a
Europe finds transgenic food hard to swallow p116
Jim Giles
doi:10.1038/424116b
Survey reveals mixed feelings over scientific misconduct p117
Alison Abbott and Phillip Graf
doi:10.1038/424117a
Europe split over move to loosen stem-cell regulations p117
Alison Abbott
doi:10.1038/424117b
Drive for patent-free innovation gathers pace p118
Declan Butler
doi:10.1038/424118a
Malaysia puts biovalley under wraps p118
David Cyranoski
doi:10.1038/424118b
DNA-chip firm backs down over upgrade p119
John Whitfield
doi:10.1038/424119a
UK shock tactics repel animal-rights activists in Japan p119
David Cyranoski
doi:10.1038/424119b
News Feature
SARS: What have we learned? p121
It's less than four months since the World Health Organization issued global warnings about a mysterious and deadly form of pneumonia. Nature's reporters pose key questions about the outbreak, and assess our preparedness to deal with future viral threats.
doi:10.1038/424121a
Correspondence
History and science united to vindicate Perutz p127
A generous team player, he was backed by colleagues in clearing his name over DNA.
Marta Paterlini
doi:10.1038/424127a
Were Cro-Magnons too like us for DNA to tell? p127
Guido Barbujani and Giorgio Bertorelle
doi:10.1038/424127b
Multitude of reference styles delays publication p127
David M. Leslie, Jr and Meredith J. Hamilton
doi:10.1038/424127c
Writing: visuals are another story p128
Marek H. Dominiczak and Kathy McFall
doi:10.1038/424128a
Writing: LEX and flexibility p128
Ava Brent
doi:10.1038/424128b
Writing: the clear choice p128
Sheila McCormick
doi:10.1038/424128c
Commentary
Hydrogen lifts off — with a heavy load p129
The dream of clean, usable energy needs to reflect practical reality.
doi:10.1038/424129a
Books and Arts
A dish to die for p131
Apes are still killed for their meat, but awareness of their plight is growing.
Guy Cowlishaw reviews Eating Apes by Dale Petersen
doi:10.1038/424131a
Design of paradise p132
Lawren Sack and Dina Dechmann review A Magic Web by Egbert Giles Leigh, Jr and Christian Ziegler
doi:10.1038/424132a
Sex on the brain p132
Joyce F. Benenson reviews Essential Difference: Men, Women and the Extreme Male Brain/ Essential Difference: The Truth About the Male and Female Brain by Simon Baron-Cohen
doi:10.1038/424132b
Science in culture p133
Colin Martin reviews
doi:10.1038/424133a
News and Views
Chemistry: Catalyst hunt accelerates p135
High-throughput methods of synthesis and analysis are streamlining the search for new catalysts, reducing the timescale from years to days. A new class of polymerization catalysts is the latest discovery.
Virgil Percec
doi:10.1038/424135a
HIV: Cross-talk and viral reservoirs p136
Even after intensive antiviral treatment, HIV-1 can lurk in reservoirs in the human body and then reappear. The complex pathways by which the virus creates such reservoirs are only now becoming clear.
Roger J. Pomerantz
doi:10.1038/424136a
Planetary science: Pluto's atmospheric surprise p137
Last year, for the first time in 14 years, an alignment of stars with Pluto created an opportunity to observe the atmosphere of this most remote of planets. Though tenuous, the atmosphere has, remarkably, expanded.
William Hubbard
doi:10.1038/424137a
Cell biology: The molecules that make muscle p138
The role of integrin proteins in the formation of skeletal muscle has been hotly debated, as studies of whole animals and of cultured cells have yielded conflicting results. The controversy may now be resolved.
Donald Gullberg
doi:10.1038/424138a
100 and 50 years ago p139
doi:10.1038/424139a
Tumour suppressors: Timing will tell p140
A sophisticated model of the effects of mutating the retinoblastoma gene reveals a window of opportunity in which cells can be released from the normal control of proliferation, before back-up mechanisms take effect.
Anton Berns
doi:10.1038/424140a
Oceanography: Stirring times in the Atlantic p141
Set against certain other oceanographic phenomena in the northwest Atlantic, a class of brief and localized events that occur in the Irminger Sea may seem inconsequential. Not so, however.
Bob Dickson
doi:10.1038/424141a
News and views in brief p143
doi:10.1038/424143a
Brief Communications
Social hierarchies: Size and growth modification in clownfish p145
Sex change is not the only way these fish achieve dominance — they grow into the role.
Peter Buston
doi:10.1038/424145a
First paragraph | Full Text | PDF (132K)
Hydrogen bonding: Single enantiomers from a chiral-alcohol catalyst p146
Yong Huang, Aditya K. Unni, Avinash N. Thadani and Viresh H. Rawal
doi:10.1038/424146a
First paragraph | Full Text | PDF (70K) | Supplementary information
Review
Transcription regulation and animal diversity p147
Michael Levine and Robert Tjian
doi:10.1038/nature01763
Abstract | Full Text | PDF (332K)
Articles
Deep convection in the Irminger Sea forced by the Greenland tip jet p152
Robert S. Pickart, Michael A. Spall, Mads Hvid Ribergaard, G. W. K. Moore and Ralph F. Milliff
doi:10.1038/nature01729
Abstract | Full Text | PDF (552K)
See also: News and Views by Dickson
The DNA sequence of human chromosome 7 p157
LaDeana W. Hillier, Robert S. Fulton, Lucinda A. Fulton, Tina A. Graves, Kymberlie H. Pepin, Caryn Wagner-McPherson, Dan Layman, Jason Maas, Sara Jaeger, Rebecca Walker, Kristine Wylie, Mandeep Sekhon, Michael C. Becker, Michelle D. O'Laughlin, Mark E. Schaller, Ginger A. Fewell, Kimberly D. Delehaunty, Tracie L. Miner, William E. Nash, Matt Cordes, Hui Du, Hui Sun, Jennifer Edwards, Holland Bradshaw-Cordum, Johar Ali, Stephanie Andrews, Amber Isak, Andrew VanBrunt, Christine Nguyen, Feiyu Du, Betty Lamar, Laura Courtney, Joelle Kalicki, Philip Ozersky, Lauren Bielicki, Kelsi Scott, Andrea Holmes, Richard Harkins, Anthony Harris, Cynthia Madsen Strong, Shunfang Hou, Chad Tomlinson, Sara Dauphin-Kohlberg, Amy Kozlowicz-Reilly, Shawn Leonard, Theresa Rohlfing, Susan M. Rock, Aye-Mon Tin-Wollam, Amanda Abbott, Patrick Minx, Rachel Maupin, Catrina Strowmatt, Phil Latreille, Nancy Miller, Doug Johnson, Jennifer Murray, Jeffrey P. Woessner, Michael C. Wendl, Shiaw-Pyng Yang, Brian R. Schultz, John W. Wallis, John Spieth, Tamberlyn A. Bieri, Joanne O. Nelson, Nicolas Berkowicz, Patricia E. Wohldmann, Lisa L. Cook, Matthew T. Hickenbotham, James Eldred, Donald Williams, Joseph A. Bedell, Elaine R. Mardis, Sandra W. Clifton, Stephanie L. Chissoe, Marco A. Marra, Christopher Raymond, Eric Haugen, Will Gillett, Yang Zhou, Rose James, Karen Phelps, Shawn Iadanoto, Kerry Bubb, Elizabeth Simms, Ruth Levy, James Clendenning, Rajinder Kaul, W. James Kent, Terrence S. Furey, Robert A. Baertsch, Michael R. Brent, Evan Keibler, Paul Flicek, Peer Bork, Mikita Suyama, Jeffrey A. Bailey, Matthew E. Portnoy, David Torrents, Asif T. Chinwalla, Warren R. Gish, Sean R. Eddy, John D. McPherson, Maynard V. Olson, Evan E. Eichler, Eric D. Green, Robert H. Waterston and Richard K. Wilson
doi:10.1038/nature01782
Abstract | Full Text | PDF (502K) | Supplementary information
Letters to Nature
The recent expansion of Pluto's atmosphere p165
J. L. Elliot, A. Ates, B. A. Babcock, A. S. Bosh, M. W. Buie, K. B. Clancy, E. W. Dunham, S. S. Eikenberry, D. T. Hall, S. D. Kern, S. K. Leggett, S. E. Levine, D.-S. Moon, C. B. Olkin, D. J. Osip, J. M. Pasachoff, B. E. Penprase, M. J. Person, S. Qu, J. T. Rayner, L. C. Roberts, Jr, C. V. Salyk, S. P. Souza, R. C. Stone, B. W. Taylor, D. J. Tholen, J. E. Thomas-Osip, D. R. Ticehurst and L. H. Wasserman
doi:10.1038/nature01762
First paragraph | Full Text | PDF (274K) | Supplementary information
See also: News and Views by Hubbard
Large changes in Pluto's atmosphere as revealed by recent stellar occultations p168
B. Sicardy, T. Widemann, E. Lellouch, C. Veillet, J.-C. Cuillandre, F. Colas, F. Roques, W. Beisker, M. Kretlow, A.-M. Lagrange, E. Gendron, F. Lacombe, J. Lecacheux, C. Birnbaum, A. Fienga, C. Leyrat, A. Maury, E. Raynaud, S. Renner, M. Schultheis, K. Brooks, A. Delsanti, O. R. Hainaut, R. Gilmozzi, C. Lidman, J. Spyromilio, M. Rapaport, P. Rosenzweig, O. Naranjo, L. Porras, F. Díaz, H. Calderón, S. Carrillo, A. Carvajal, E. Recalde, L. Gaviria Cavero, C. Montalvo, D. Barría, R. Campos, R. Duffard and H. Levato
doi:10.1038/nature01766
First paragraph | Full Text | PDF (203K)
See also: News and Views by Hubbard
Miniaturized gas ionization sensors using carbon nanotubes p171
Ashish Modi, Nikhil Koratkar, Eric Lass, Bingqing Wei and Pulickel M. Ajayan
doi:10.1038/nature01777
First paragraph | Full Text | PDF (281K) | Supplementary information
Unidirectional rotation in a mechanically interlocked molecular rotor p174
David A. Leigh, Jenny K. Y. Wong, François Dehez and Francesco Zerbetto
doi:10.1038/nature01758
First paragraph | Full Text | PDF (728K) | Supplementary information
Post-earthquake ground movements correlated to pore-pressure transients p179
Sigurjón Jónsson, Paul Segall, Rikke Pedersen and Grímur Björnsson
doi:10.1038/nature01776
First paragraph | Full Text | PDF (1,314K)
Urbanization effects on tree growth in the vicinity of New York City p183
Jillian W. Gregg, Clive G. Jones and Todd E. Dawson
doi:10.1038/nature01728
First paragraph | Full Text | PDF (309K)
Strong population substructure is correlated with morphology and ecology in a migratory bat p187
Cassandra M. Miller-Butterworth, David S. Jacobs and Eric H. Harley
doi:10.1038/nature01742
First paragraph | Full Text | PDF (296K) | Supplementary information
Captivity masks inbreeding effects on male mating success in butterflies p191
Mathieu Joron and Paul M. Brakefield
doi:10.1038/nature01713
First paragraph | Full Text | PDF (191K) | Supplementary information
Dosage sensitivity and the evolution of gene families in yeast p194
Balázs Papp, Csaba Pál and Laurence D. Hurst
doi:10.1038/nature01771
First paragraph | Full Text | PDF (166K) | Supplementary information
Widespread horizontal transfer of mitochondrial genes in flowering plants p197
Ulfar Bergthorsson, Keith L. Adams, Brendan Thomason and Jeffrey D. Palmer
doi:10.1038/nature01743
First paragraph | Full Text | PDF (703K) | Supplementary information
Topography and synaptic shaping of direction selectivity in primary auditory cortex p201
Li I. Zhang, Andrew Y. Y. Tan, Christoph E. Schreiner and Michael M. Merzenich
doi:10.1038/nature01796
First paragraph | Full Text | PDF (2,464K) | Supplementary information
Glutamate-receptor-mediated encoding and retrieval of paired-associate learning p205
M. Day, R. Langston and R. G. M. Morris
doi:10.1038/nature01769
First paragraph | Full Text | PDF (283K) | Supplementary information
T-type calcium channel regulation by specific G-protein 
subunits p209
Joshua T. Wolfe, Hongge Wang, Jason Howard, James C. Garrison and Paula Q. Barrett
doi:10.1038/nature01772
First paragraph | Full Text | PDF (814K)
HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection p213
Simon Swingler, Beda Brichacek, Jean-Marc Jacque, Catherine Ulich, Jin Zhou and Mario Stevenson
doi:10.1038/nature01749
First paragraph | Full Text | PDF (459K)
See also: News and Views by Pomerantz
JNK phosphorylates paxillin and regulates cell migration p219
Cai Huang, Zenon Rajfur, Christoph Borchers, Michael D. Schaller and Ken Jacobson
doi:10.1038/nature01745
First paragraph | Full Text | PDF (607K) | Supplementary information
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry p223
Julien Sage, Abigail L. Miller, Pedro A. Pérez-Mancera, Julianne M. Wysocki and Tyler Jacks
doi:10.1038/nature01764
First paragraph | Full Text | PDF (320K) | Supplementary information
See also: News and Views by Berns
Xpd/Ercc2 regulates CAK activity and mitotic progression p228
Jian Chen, Stéphane Larochelle, Xiaoming Li and Beat Suter
doi:10.1038/nature01746
First paragraph | Full Text | PDF (405K) | Supplementary information
Naturejobs
ProspectsScience rocks p233
Paul Smaglik
doi:10.1038/nj6945-233a
POSTDOCS
The learning curve p234
Students starting their PhD and postdocs moving into fresh areas of research often find themselves in need of different technical skills. How does everyone get up to speed? Karen Kreeger reports.
Karen Kreeger
doi:10.1038/nj6945-234a
