Even after intensive antiviral treatment, HIV-1 can lurk in reservoirs in the human body and then reappear. The complex pathways by which the virus creates such reservoirs are only now becoming clear.
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Pomerantz, R. Cross-talk and viral reservoirs. Nature 424, 136–137 (2003). https://doi.org/10.1038/424136a
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DOI: https://doi.org/10.1038/424136a