Access

News and Views

Nature 424, 21-22 (3 July 2003) | doi:10.1038/424021a

Open Innovation Challenges

  • Methods to Analyze Consumer Emotions

    • Deadline: Jan 17 2010
    • Reward: $10,000 USD

    The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ...

  • Single-cell Analysis Platform

    • Deadline: Dec 02 2009
    • Reward: $5,000 USD

    This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...

naturejobs

More science jobs
Post a job for free

Good to CU

Yapeng Gu & Wesley I. Sundquist

Top

A powerful arm of the cellular defence against microbial invaders has been characterized. APOBEC3G, a protein that can fight off HIV, works by introducing 'typographical errors' during viral replication.

HIV encodes a protein that allows the virus to multiply in otherwise resistant human cells1, 2, 3. This protein, Vif — for 'viral infectivity factor' — works by overcoming a cellular protein, APOBEC3G, whose task is to inhibit the replication of HIV and other retroviruses4.

  1. Yapeng Gu and Wesley I. Sundquist are in the Department of Biochemistry, University of Utah, Salt Lake City, Utah 84132, USA.

Correspondence to: Wesley I. Sundquist e-mail: Email: wes@biochem.utah.edu