Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 423, 818-819 (19 June 2003) | doi:10.1038/423818b
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
- More Challenges
- Powered by:
nature jobs
Postdoctoral Research Associate
- Rice University
- Houston, Texas, USA
Apply for PhD Program
- Shinshu University
- Ueda, Nagano 386-8567 Japan
Cell cycle: Degradation ensures integrity
Anatoliy Li & J. Julian Blow
Abstract
Protein degradation terminates a range of biochemical activities in living cells. New work shows that a component of the 'licensing' system for DNA replication must be degraded to prevent re-replication during cell division.
How would you ensure that a biochemical reaction is irreversible? This is a key problem in living organisms, because many of their control systems must progress unidirectionally through a series of different states.
- Anatoliy Li and J. Julian Blow are in the Cancer Research UK Chromosome Replication Research Group, Wellcome Trust Biocentre, University of Dundee, Dundee DD1 5EH, UK.
Correspondence to: J. Julian Blow e-mail: Email: j.j.blow@dundee.ac.uk
To read this story in full you will need to login or make a payment (see right).
