FIGURE 1. Sequence comparison of human and ape MSY palindromes.

a, Nucleotide sequences of inner boundaries of palindrome P6 in human and apes. Dots represent identity to human sequence. Full interspecific alignments of this and other palindromes' boundaries are in Supplementary Information. b, Overview of sequence divergence between human and chimpanzee palindromes, and between palindrome arms within each species. Each palindrome is shown to scale, folded about the centre of the spacer. For palindromes P1/P2 and P6, only the central portions are contained in sequenced chimpanzee BACs, and the palindromes are not perfectly centred within the BACs. Therefore, more sequence from one arm is available than from the other. For P1/P2 we include the 5' and 3' DAZ exons but exclude the central, intragenically duplicated regions of the gene²⁴). The CDY1 genes are not in the portions of P1 shown¹. For palindrome P7, the entire sequence of both arms is represented in sequenced chimpanzee BACs, as is extensive flanking, non-ampliconic sequence. Supplementary Table 8 provides confidence intervals, calculations and links to sequence alignments.