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Nature 423, 591-592 (5 June 2003) |

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Neurobiology: All change at the synapse

Silvio O. Rizzoli & William J. Betz

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Two groups, using different approaches, have provided the first quantitative evidence that neurotransmitter release in the brain often occurs by a long-sought 'kiss-and-run' process.

Synaptic transmission — the transfer of information between nerve cells — is the most important aspect of brain function. Roughly speaking, it works as follows.

  1. Silvio O. Rizzoli and William J. Betz are in the Department of Physiology and Biophysics, University of Colorado Medical School, 4200 East Ninth Avenue, Denver, Colorado 80262, USA.

Correspondence to: William J. Betz e-mail: Email: bill.betz@uchsc.edu