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Nature 423, 488-489 (29 May 2003) |

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Chemistry: Tips for moving single molecules

Dennis C. Jacobs

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Scanning tunnelling microscopes provide a unique perspective on chemistry at the level of single molecules. Now there is a new way of using the tip of such a microscope to manipulate a single molecule.

In nature, reactants can be transformed into products through a vast array of mechanisms. In synthetic chemistry, progress hinges on finding a way to maximize the yield of the desired target molecule while minimizing the generation of unwanted by-products.