Table of contents
Volume 423 Number 6936 pp101-205
Editorials
Hope for best, prepare for worst p101
Enigmatic North Korea has government officials around the world anxious. Scientists in East Asia should be thinking about how they might be involved.
doi:10.1038/423101a
Berlin's university crisis p101
German universities must take drastic decisions, to pursue a more flexible approach to education and research.
doi:10.1038/423101b
News
France purges space programme in bid to survive budget crisis p103
Declan Butler
doi:10.1038/423103a
US Army joins hunt for SARS drug p103
Alison Abbott
doi:10.1038/423103b
US fails to quantify threat of West Nile virus p104
Hannah Hoag
doi:10.1038/423104a
Los Alamos contract open to bids p104
Geoff Brumfiel
doi:10.1038/423104b
Geneticists question fees for use of patented 'junk' DNA p105
Carina Dennis
doi:10.1038/423105a
Physicist takes the reins at Santa Fe complexity centre p105
Geoff Brumfiel
doi:10.1038/423105b
Homeland science chief wants quick fixes p106
Erika Check
doi:10.1038/423106a
Dying cells dragged screaming under the microscope p106
Catherine Zandonella
doi:10.1038/423106b
AIDS researchers seek criteria for vaccines p107
Erika Check
doi:10.1038/423107a
news feature
Weapons proliferation: Asia's nuclear family p110
If North Korea has nuclear weapons, its neighbours may want to develop their own. Geoff Brumfiel and David Cyranoski ask whether Japanese and South Korean scientists would answer a call to nuclear arms.
David Cyranoski and Geoff Brumfiel
doi:10.1038/423110a
Spinal injuries: In search of a miracle p112
Paralysed patients are looking to scientists working on spinal-cord regeneration to help them walk again. Is this pressure causing too much faith to be placed in preliminary, inconclusive results? Helen Pearson investigates.
Helen Pearson
doi:10.1038/423112a
SARS testing: First past the post p114
From the moment the mysterious illness known as SARS was declared a global threat to health, virologists were racing to develop a diagnostic test. Alison Abbott visits the tiny German lab that got there first.
Alison Abbott
doi:10.1038/423114a
Correspondence
How technology can reduce our impact on the Earth p115
Prudent use of innovations could avoid sacrificing the present for the future, or vice versa.
Indur M. Goklany and Anthony J. Trewavas
doi:10.1038/423115a
Unbalanced view of a dynamic world p115
Graham Martin
doi:10.1038/423115b
Lack of trained security staff delays US visas p115
Edward McSweegan
doi:10.1038/423115c
Designer scientific literature p116
U. Kutschera
doi:10.1038/423116a
Peer review: recognition via year-end statements p116
A. J. (Tom) van Loon
doi:10.1038/423116b
Books and Arts
Going back to our roots p117
What can genetic techniques tell us about human origins and diversity?
Rebecca Cann reviews The Journey of Man: A Genetic Odyssey by Spencer Wells and Reflections on our Past: How Human History is Revealed in Our Genes by John H. Relethford
doi:10.1038/423117a
Crossing the species barrier p118
Richard E. Race reviews How the Cows Turned Mad by Maxime Schwartz
doi:10.1038/423118a
A collection to remember p119
Larry R. Squire reviews Memory From A to Z by Yadin Dudai
doi:10.1038/423119a
Cinema: Return of the mutants p119
Adam Rutherford
doi:10.1038/423119b
News and Views
Planetary Science: Catch a falling star p123
The European Fireball Network has recovered a meteorite after photographing its violent entry into the Earth's atmosphere. This is only the fourth such recovery, and analysis points to a surprising past for this primitive object.
Jack Drummond
doi:10.1038/423123a
Mathematics: Conjuring with conjectures p124
The Clay Mathematics Institute is offering a million dollars for a solution to the Poincaré conjecture, and Grisha Perelman may have found one. What is the conjecture, and why does it matter?
Ian Stewart
doi:10.1038/423124a
Molecular physiology: Tuned for longer life p125
Richard Turner
doi:10.1038/423125a
Prion diseases: Cannibals and garbage piles p127
There's a lot of disagreement among prion scientists, as a recent conference made very clear. Even the revered 'prion hypothesis' came under attack.
Adriano Aguzzi and Mathias Heikenwalder
doi:10.1038/423127a
100 and 50 years ago p127
doi:10.1038/423127b
Animal behaviour: Homing is a breeze for sea turtles p128
David W. Sims
doi:10.1038/423128a
Cell biology: Patches for wounded muscle p129
The stresses and strains imposed on certain cells mean that their membranes require constant repair. Study of the damage that affects muscle membranes reveals a new component of the repair process.
Juliet A. Ellis
doi:10.1038/423129a
Complex fluids: Spread the word about nanofluids p131
Liquid spreads and wets a surface, but wetting behaviour changes if the liquid contains nanoparticles. New experiments point to an explanation and a way to create effective detergents for cleaning oil from a surface.
Manoj K. Chaudhury
doi:10.1038/423131a
Computational biology: Biosensor design p132
A series of bacterial receptor proteins have been 'redesigned' by computer so that they bind molecules that are quite different from their natural ligands. The approach might be useful for designing catalytic proteins.
William F. DeGrado
doi:10.1038/423132a
news and view in brief p134
doi:10.1038/423134a
Brief Communications
Palaeontology: A fly in the biogeographic ointment p135
A tiny fossil provides a clue as to how things were in Antarctica millions of years ago.
Allan C. Ashworth and F. Christian Thompson
doi:10.1038/423135a
First paragraph | Full Text | PDF (163K)
Electronic paper: Flexible active-matrix electronic ink display p136
Y. Chen, J. Au, P. Kazlas, A. Ritenour, H. Gates and M. McCreary
doi:10.1038/423136a
First paragraph | Full Text | PDF (298K)
Comparative genomics: Insecticide resistance in mosquito vectors p136
Mylène Weill, Georges Lutfalla, Knud Mogensen, Fabrice Chandre, Arnaud Berthomieu, Claire Berticat, Nicole Pasteur, Alexandre Philips, Philippe Fort and Michel Raymond
doi:10.1038/423136b
First paragraph | Full Text | PDF (298K) | Supplementary information
Nitrogen storage (communication arising): UV-B radiation and soil microbial communities p137
John M. Stark and Stephen C. Hart
doi:10.1038/423137a
First paragraph | Full Text | PDF (81K)
Nitrogen storage (communication arising): UV-B radiation and soil microbial communities p138
David Johnson, Colin D. Campbell, John A. Lee, Terry V. Callaghan and Dylan Gwynn-Jones
doi:10.1038/423138a
First paragraph | Full Text | PDF (65K)
Articles
The evolutionary origin of complex features p139
Richard E. Lenski, Charles Ofria, Robert T. Pennock and Christoph Adami
doi:10.1038/nature01568
Abstract | Full Text | PDF (285K) | Supplementary information
The structure of DNA in the nucleosome core p145
Timothy J. Richmond and Curt A. Davey
doi:10.1038/nature01595
Abstract | Full Text | PDF (424K) | Supplementary information
Letters to Nature
Photographic observations of Neuschwanstein, a second meteorite from the orbit of the P
íbram chondrite p151
Pavel Spurný, Jürgen Oberst and Dieter Heinlein
doi:10.1038/nature01592
First paragraph | Full Text | PDF (228K)
See also: News and Views by Drummond
Controlled vesicle deformation and lysis by single oscillating bubbles p153
Philippe Marmottant and Sascha Hilgenfeldt
First paragraph | Full Text | PDF (359K) | Supplementary information
Spreading of nanofluids on solids p156
Darsh T. Wasan and Alex D. Nikolov
doi:10.1038/nature01591
First paragraph | Full Text | PDF (597K) | Supplementary information
See also: News and Views by Chaudhury
Redistribution of energy available for ocean mixing by long-range propagation of internal waves p159
Matthew H. Alford
doi:10.1038/nature01628
First paragraph | Full Text | PDF (617K)
Experimental evidence that potassium is a substantial radioactive heat source in planetary cores p163
V. Rama Murthy, Wim van Westrenen and Yingwei Fei
doi:10.1038/nature01560
First paragraph | Full Text | PDF (203K) | Supplementary information
Universal scaling relations in food webs p165
Diego Garlaschelli, Guido Caldarelli and Luciano Pietronero
doi:10.1038/nature01604
First paragraph | Full Text | PDF (210K)
Defective membrane repair in dysferlin-deficient muscular dystrophy p168
Dimple Bansal, Katsuya Miyake, Steven S. Vogel, Séverine Groh, Chien-Chang Chen, Roger Williamson, Paul L. McNeil and Kevin P. Campbell
First paragraph | Full Text | PDF (463K) | Supplementary information
See also: News and Views by Ellis
Identification of Vangl2 and Scrb1 as planar polarity genes in mammals p173
Mireille Montcouquiol, Rivka A. Rachel, Pamela J. Lanford, Neal G. Copeland, Nancy A. Jenkins and Matthew W. Kelley
doi:10.1038/nature01618
First paragraph | Full Text | PDF (726K)
Pathogenic bacteria attach to human fibronectin through a tandem 
-zipper p177
Ulrich Schwarz-Linek, Jörn M. Werner, Andrew R. Pickford, Sivashankarappa Gurusiddappa, Jung Hwa Kim, Ewa S. Pilka, John A. G. Briggs, T. Sebastian Gough, Magnus Höök, Iain D. Campbell and Jennifer R. Potts
doi:10.1038/nature01589
First paragraph | Full Text | PDF (472K)
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae p181
Rozalyn M. Anderson, Kevin J. Bitterman, Jason G. Wood, Oliver Medvedik and David A. Sinclair
First paragraph | Full Text | PDF (470K)
See also: News and Views by Turner
Computational design of receptor and sensor proteins with novel functions p185
Loren L. Looger, Mary A. Dwyer, James J. Smith and Homme W. Hellinga
doi:10.1038/nature01556
First paragraph | Full Text | PDF (445K) | Supplementary information
See also: News and Views by DeGrado
Direct observation of catch bonds involving cell-adhesion molecules p190
Bryan T. Marshall, Mian Long, James W. Piper, Tadayuki Yago, Rodger P. McEver and Cheng Zhu
doi:10.1038/nature01605
First paragraph | Full Text | PDF (448K)
Folding at the speed limit p193
Wei Yuan Yang and Martin Gruebele
doi:10.1038/nature01609
First paragraph | Full Text | PDF (372K) | Supplementary information
corrigendum: Synaptic depression in the localization of sound p197
Daniel L. Cook, Peter C. Schwindt, Lucinda A. Grande and William J. Spain
doi:10.1038/nature01561
corrigendum: Short interfering RNA confers intracellular antiviral immunity in human cells p197
Leonid Gitlin, Sveta Karelsky and Raul Andino
doi:10.1038/nature01562
erratum: Antibody neutralization and escape by HIV-1 p197
Xiping Wei, Julie M. Decker, Shuyi Wang, Huxiong Hui, John C. Kappes, Xiaoyun Wu, Jesus F. Salazar-Gonzalez, Maria G. Salazar, J. Michael Kilby, Michael S. Saag, Natalia L. Komarova, Martin A. Nowak, Beatrice H. Hahn, Peter D. Kwong and George M. Shaw
doi:10.1038/nature01565
New on the Market
Microbiology miscellany p199
Bugs, cells, counts and sample preparation.
doi:10.1038/423199a
Naturejobs
ProspectsCash crisis in the corridor p203
Paul Smaglik
doi:10.1038/nj6936-203a
SPECIAL REPORT
A fresh outlook for eastern Germany p204
Science has flourished in eastern Germany since reunification, bringing researchers from far and near. But the tide of investment may be turning. Marieke Degen reports.
Marieke Degen
doi:10.1038/nj6936-204a
