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Nature 423, 127-129 (8 May 2003) | doi:10.1038/423127a

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Prion diseases: Cannibals and garbage piles

Adriano Aguzzi1 & Mathias Heikenwalder1

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There's a lot of disagreement among prion scientists, as a recent conference made very clear. Even the revered 'prion hypothesis' came under attack.

After more than 280,000 mad cows and two Nobel prizes for research on transmissible spongiform encephalopathies, we must know all there is to know about these 'prion' diseases. Or do we?

  1. Adriano Aguzzi and Mathias Heikenwalder are at the Institute of Neuropathology, University Hospital of Zurich, CH-8091 Zurich, Switzerland.

Correspondence to: Adriano Aguzzi1 e-mail: Email: adriano.aguzzi@usz.ch