Figures and Tables
From the following article:
The principle of gating charge movement in a voltage-dependent K+ channel
Youxing Jiang, Vanessa Ruta, Jiayun Chen, Alice Lee and Roderick MacKinnon
Nature 423, 42-48(1 May 2003)
doi:10.1038/nature01581
Figure 1
Inhibition of KvAP channels by Fabs and a tarantula venom toxin that bind to the voltage-sensor paddles.
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Figure 2
Using avidin and tethered biotin as a molecular ruler to measure positions of the voltage-sensor paddles.
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Figure 3
Accessibility of voltage-sensor paddle residues to the internal and external sides of the membrane.
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Figure 4
Exposure of the voltage-sensor paddle to the external solution occurs only when the membrane is depolarized.
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Figure 5
Positions within the membrane of the voltage-sensor paddles during closed and opened conformations, and a hypothesis for coupling to pore opening.
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