Supplementary information

From the following article:

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

Shuang-Xi Ren, Gang Fu, Xiu-Gao Jiang, Rong Zeng, You-Gang Miao, Hai Xu, Yi-Xuan Zhang, Hui Xiong, Gang Lu, Ling-Feng Lu, Hong-Quan Jiang, Jia Jia, Yue-Feng Tu, Ju-Xing Jiang, Wen-Yi Gu, Yue-Qing Zhang, Zhen Cai, Hai-Hui Sheng, Hai-Feng Yin, Yi Zhang, Gen-Feng Zhu, Ma Wan, Hong-Lei Huang, Zhen Qian, Sheng-Yue Wang, Wei Ma, Zhi-Jian Yao, Yan Shen, Bo-Qin Qiang, Qi-Chang Xia, Xiao-Kui Guo, Antoine Danchin, Isabelle Saint Girons, Ronald L. Somerville, Yu-Mei Wen, Man-Hua Shi, Zhu Chen, Jian-Guo Xu and Guo-Ping Zhao

Nature 422, 888-893(24 April 2003)

doi:10.1038/nature01597

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Supplementary information 1: Schematic illustration of the putative replication origins of (a) CI and (b) CII of L. interrogans strain Lai. Genes related to the replication origins of CI and CII are listed

Supplementary information 2-1: Tabulated information about tRNA genes in the genome of L. interrogans stain Lai
Supplementary information 2-2: Predicted CDSs corresponding to genes discussed in the text or illustrated in Fig. 2

Supplementary information 3: Functional categories and orthologs of L. interrogans predicted genes

Supplementary information 4: Schematic illustration of functional assignment to some hypothetical proteins based on their structural characteristics.
Supplementary information 4-1: Schematic illustration of functional assignment to CheY based on secondary structure prediction and comparison on hypothetical proteins.
Supplementary information 4-2 (A-E): Schematic illustration of functional assignment to genes encoding key enzymes for LPS biosynthesis based on prediction of protein transmembrane domains.
Supplementary information 4-3: Amino acid sequence comparison of the hypothetical UDP-N-acetylglucosamine acyltransferase (LpxA, LA3949) of L. interrogans to those of E. coli and Pseudomonas.

Supplementary information 5: The rfb locus of L. interrogans serovar lai with predicted CDSs.

Supplementary information 6: The lipidA biosynthesis genes of L. interrogans serovar lai.

Supplementary information 7: Hemolysin genes of L. interrogans serovar lai.

Supplementary information 8: Primary sequences and predicted secondary structures for PafAH (A), Vwa (B), and Pon (C).

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