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Nature 422, 272-273 (20 March 2003) | doi:10.1038/422272a

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Developmental biology: A hairy situation

Yann Barrandon

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A key step in hair-follicle development is the rearrangement of epithelial stem cells. It seems that reduced production of an adhesion protein, through the concerted action of two signalling pathways, is crucial for this process.

It's often difficult to tell when two people are siblings — despite their common origins and upbringing, they are usually very different. Similarly, it is not always obvious when distinct cell types have been produced from the same precursor cells.