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Nature 422, 269-270 (20 March 2003) | doi:10.1038/422269a
Genomics: Gene expression meets genetics
Ariel Darvasi
Abstract
Genetic analyses look for differences in gene sequence that could explain variation in physical traits. Gene-expression studies provide a snapshot of active genes. These approaches are now combined, to great effect.
There is an undeclared dispute among researchers who study complex traits — physical or behavioural characteristics of an organism that are dictated by combinations of more than one gene and the environment. On one side are classical geneticists, who look at the differences in DNA sequence between individuals and attempt to correlate them with physical and behavioural variations.
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