Table of contents
Volume 421 Number 6926 pp875-973
Editorial
Sacrifice for the greater good? p875
Genome sequencers intend that their community and others should deposit data in community databases immediately, even if it risks the loss of publishing priority. But enforcement of this ideal could be a step too far.
doi:10.1038/421875a
News
Draft guidelines ease restrictions on use of genome sequence data p877
Carina Dennis
doi:10.1038/421877a
Mixed results win HIV vaccine a guarded response p877
Hannah Hoag
doi:10.1038/421877b
Physicists fail to find saving grace for falsified research p878
Philip Ball
doi:10.1038/421878a
NASA seeks inspiration from microscopic views of life p878
Jonathan Knight
doi:10.1038/421878b
Climate panel to seize political hot potatoes p879
Quirin Schiermeier
doi:10.1038/421879a
Experts cast doubt on Britain's green energy ambitions p879
Natasha McDowell
doi:10.1038/421879b
Genomes take pole position in the icy wastes p880
Hannah Hoag
doi:10.1038/421880a
Canada boosts spending on science p880
David Spurgeon
doi:10.1038/421880b
NASA pins hopes on nuclear-powered orbiter p881
Tony Reichhardt
doi:10.1038/421881a
Europe draws up plans for funding agency p881
Marieke Degen
doi:10.1038/421881b
news feature
Tissue engineering: The beat goes on p884
Four years ago, scientists claimed they would grow a functioning heart in the lab within a decade. That now looks like wishful thinking, but Catherine Zandonella finds that tissue engineers haven't given up on their grand vision.
Catherine Zandonella
doi:10.1038/421884a
Disaster planning: Avalanche! p887
High in the Swiss Alps, a multidisciplinary group of researchers is developing a feeling for snow. Quirin Schiermeier meets the avalanche forecasters.
Quirin Schiermeier
doi:10.1038/421887a
Correspondence
Switzerland's role as a hotspot of type specimens p889
Up to a quarter of all the world's species can be found in one small, landlocked country.
Donat Agosti, Peter Linder, Daniel Burckhardt, Sylvia Martinez, Ivan Löbl and Pierre André Loizeau
doi:10.1038/421889a
Novel and conventional paths to a better banana p889
David Jones
doi:10.1038/421889b
Objective assessment of transgenic salmon p889
George Gray
doi:10.1038/421889c
Commentary
Liability for climate change p891
Will it ever be possible to sue anyone for damaging the climate?
doi:10.1038/421891a
Book Reviews
Feeling emotional p893
What can a seventeenth-century philosopher possibly tell us about emotion?
Ray Dolan reviews Looking for Spinoza: Joy, Sorrow and the Feeling Brain by Antonio Damasio
doi:10.1038/421893a
Riding the solar wind p894
James A. Klimchuk reviews Journey From the Center of the Sun by Jack B. Zirker
doi:10.1038/421894a
Keeping up with evolution p895
Joel Peck reviews Encyclopedia of Evolution
doi:10.1038/421895a
A natural harbour p895
doi:10.1038/421895b
News and Views
Gravity: The weight of expectation p899
Newton devised his universal law of gravitation for planets, but does it work at small scales? A search for a deviation from the expected behaviour could provide the first evidence in support of string theory.
C. D. Hoyle
doi:10.1038/421899a
Ecology: The how and why of biodiversity p900
A study of reef fish in the Indian and Pacific oceans reveals that the structures of local communities and their regional context are intricately entwined. New species spread far from an oceanic 'hotspot' of diversity.
Kevin J. Gaston
doi:10.1038/421900a
Geochemistry: Lost terrains of early Earth p901
Isotope data provide insight into the earliest phases of terrestrial evolution. The latest reappraisal supports the view that the early Earth had a cratered crust which crystallized from a magma ocean.
Stein B. Jacobsen
doi:10.1038/421901a
100 and 50 years ago p901
doi:10.1038/421901b
Developmental biology: A twist in a mouse tale p903
Studies of the retinoblastoma gene can still deliver surprises, and enlightenment. Several of the abnormalities in mice lacking this gene are, it seems, the indirect consequence of a placental defect.
Nick Dyson
doi:10.1038/421903a
Oceanography: The brawniest retroflection p904
The influence of the Agulhas system of currents and eddies around southern Africa extends far beyond that region. Hence the especial need for a better understanding of the complex phenomena involved.
Arnold L. Gordon
doi:10.1038/421904a
Cell polarity: From embryo to axon p905
Many cell types in our body, ranging from neurons to the epithelial cells that line the lungs and skin, must be polarized to function properly. The same mechanism may establish the polarity of many of these cells.
Melissa M. Rolls and Chris Q. Doe
doi:10.1038/421905a
news and views in brief p907
doi:10.1038/421907a
Brief Communications
Environment: A pre-industrial source of dioxins and furans p909
Domestic burning of coastal peat has produced these nasty pollutants for millennia.
Andrew A. Meharg and Kenneth Killham
doi:10.1038/421909a
First paragraph | Full Text | PDF (102K)
Sociobiology: Worker nepotism among polygynous ants p910
Minttumaaria Hannonen and Liselotte Sundström
doi:10.1038/421910a
First paragraph | Full Text | PDF (85K)
Audiovisual perception: Implicit estimation of sound-arrival time p911
Yoichi Sugita and Yôiti Suzuki
doi:10.1038/421911a
First paragraph | Full Text | PDF (79K)
Sociology (communication arising): The puzzle of human cooperation p911
Dominic D. P. Johnson, Pavel Stopka and Stephen Knights
doi:10.1038/421911b
First paragraph | Full Text | PDF (79K)
Sociology (communication arising (reply)): The puzzle of human cooperation p912
Ernst Fehr and Simon Gächter
doi:10.1038/421912a
First paragraph | Full Text | PDF (56K)
Review
Fire science for rainforests p913
Mark A. Cochrane
doi:10.1038/nature01437
Abstract | Full Text | PDF (467K)
Letters to Nature
Energetic neutral atoms from a trans-Europa gas torus at Jupiter p920
B. H. Mauk, D. G. Mitchell, S. M. Krimigis, E. C. Roelof and C. P. Paranicas
doi:10.1038/nature01431
First paragraph | Full Text | PDF (885K)
Upper limits to submillimetre-range forces from extra space-time dimensions p922
Joshua C. Long, Hilton W. Chan, Allison B. Churnside, Eric A. Gulbis, Michael C. M. Varney and John C. Price
doi:10.1038/nature01432
First paragraph | Full Text | PDF (240K)
See also: News and Views by Hoyle
Ultra-high-Q toroid microcavity on a chip p925
D. K. Armani, T. J. Kippenberg, S. M. Spillane and K. J. Vahala
doi:10.1038/nature01371
First paragraph | Full Text | PDF (282K)
Logarithmic rate dependence of force networks in sheared granular materials p928
R. R. Hartley and R. P. Behringer
doi:10.1038/nature01394
First paragraph | Full Text | PDF (356K)
Early history of Earth's crust–mantle system inferred from hafnium isotopes in chondrites p931
Martin Bizzarro, Joel A. Baker, Henning Haack, David Ulfbeck and Minik Rosing
doi:10.1038/nature01421
First paragraph | Full Text | PDF (185K) | Supplementary information
See also: News and Views by Jacobsen
Patterns and processes in reef fish diversity p933
Camilo Mora, Paul M. Chittaro, Peter F. Sale, Jacob P. Kritzer and Stuart A. Ludsin
doi:10.1038/nature01393
First paragraph | Full Text | PDF (588K)
See also: News and Views by Gaston
Mechanism of genetic exchange in American trypanosomes p936
Michael W. Gaunt, Matthew Yeo, Iain A. Frame, J. Russell Stothard, Hernan J. Carrasco, Martin C. Taylor, Susana Solis Mena, Paul Veazey, Graham A. J. Miles, Nidia Acosta, Antonieta Rojas de Arias and Michael A. Miles
doi:10.1038/nature01438
First paragraph | Full Text | PDF (309K) | Supplementary information
Water transport in plants obeys Murray's law p939
Katherine A. McCulloh, John S. Sperry and Frederick R. Adler
doi:10.1038/nature01444
First paragraph | Full Text | PDF (205K) | Supplementary information
Extra-embryonic function of Rb is essential for embryonic development and viability p942
Lizhao Wu, Alain de Bruin, Harold I. Saavedra, Maja Starovic, Anthony Trimboli, Ying Yang, Jana Opavska, Pamela Wilson, John C. Thompson, Michael C. Ostrowski, Thomas J. Rosol, Laura A. Woollett, Michael Weinstein, James C. Cross, Michael L. Robinson and Gustavo Leone
doi:10.1038/nature01417
First paragraph | Full Text | PDF (684K) | Supplementary information
See also: News and Views by Dyson
Role for antisense RNA in regulating circadian clock function in Neurospora crassa p948
Cas Kramer, Jennifer J. Loros, Jay C. Dunlap and Susan K. Crosthwaite
doi:10.1038/nature01427
First paragraph | Full Text | PDF (405K)
MDC1 is required for the intra-S-phase DNA damage checkpoint p952
Michal Goldberg, Manuel Stucki, Jacob Falck, Damien D'Amours, Dinah Rahman, Darryl Pappin, Jiri Bartek and Stephen P. Jackson
doi:10.1038/nature01445
First paragraph | Full Text | PDF (467K)
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways p957
Zhenkun Lou, Katherine Minter-Dykhouse, Xianglin Wu and Junjie Chen
doi:10.1038/nature01447
First paragraph | Full Text | PDF (468K)
MDC1 is a mediator of the mammalian DNA damage checkpoint p961
Grant S. Stewart, Bin Wang, Colin R. Bignell, A. Malcolm R. Taylor and Stephen J. Elledge
doi:10.1038/nature01446
First paragraph | Full Text | PDF (567K) | Supplementary information
New on the Market
Talk to your analyst p967
Analytical instruments and offshoots, including a new way with images.
doi:10.1038/421967a
Naturejobs
ProspectsGround control p969
Paul Smaglik
doi:10.1038/nj6926-969a
CAREERS AND RECRUITMENT
The data busters p970
Making sense of the reams of information streaming out of genome projects requires a sophisticated blend of biology and physics, says Kendall Powell.
Kendall Powell
doi:10.1038/nj6926-970a