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Nature 421, 491-492 (30 January 2003) | doi:10.1038/421491a
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Senior Scientific Manager / Chief Scientific Manager for Neuroscience Group In Vivo Pharmacology / Biology
- Syngene International
- Bangalore, Karnataka 560099 India
Assistant Professor of Medicine
- Massachusetts General Hospital
- Boston, MA
Behavioural genetics: Family matters
David Haig
Abstract
Differential activation of genes inherited from mothers and fathers will manifest itself as conflict in families. The effects are being explored experimentally with mice.
The evolution of maternal care involves a complex interplay between the genetic interests of mothers and those of offspring, with offspring predicted to favour higher levels of care than those favoured by mothers1. This interaction is further complicated by the possibility of conflict within offspring genomes through a phenomenon known as genetic imprinting2, and of conflicts within maternal genomes between genes that are inherited by a particular offspring and genes that are not3.
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