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double helix
Nature 421, 448-453 (23 January 2003) | doi:10.1038/nature01411
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Neuropathology Assistant or Associate Research Professor
- Indiana University School of Medicine
- Indiana, USA
Gastroenterologist
- Gundersen Lutheran Health System
- La Crosse, Wisconsin, USA
feature Controlling the double helix
Gary Felsenfeld1 & Mark Groudine2
Abstract
Chromatin is the complex of DNA and proteins in which the genetic material is packaged inside the cells of organisms with nuclei. Chromatin structure is dynamic and exerts profound control over gene expression and other fundamental cellular processes. Changes in its structure can be inherited by the next generation, independent of the DNA sequence itself.
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