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double helix

Nature 421, 421-422 (23 January 2003) | doi:10.1038/nature01404

feature Portrait of a molecule

Philip Ball

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The double helix is idealized for its aesthetic elegant structure, but the reality of DNA's physical existence is quite different. Most DNA in the cell is compressed into a tangled package that somehow still exposes itself to meticulous gene-regulatory control. Philip Ball holds a mirror up to what we truly know about the mysteries of DNA's life inside a cell.