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Nature 421, 310-312 (23 January 2003) | doi:10.1038/421310a

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DNA: Beyond the double helix

Helen Pearson1

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The world of science is gearing up to celebrate the 50th anniversary of Watson and Crick's seminal paper. But there's more to DNA than the pair's iconic structure. Helen Pearson profiles a truly dynamic molecule.

Every day, as a young postdoc, Susan Gasser gazed at a twisted wire skeleton of DNA that was collecting dust in her supervisor's office — a sculptural homage to Jim Watson and Francis Crick's epoch-making paper on the double helix1.But Gasser now heads a molecular biology laboratory at the University of Geneva, whose members see DNA in a very different light.