double helix
Nature 421, 409-412 (23 January 2003) | doi:10.1038/nature01400
The mosaic that is our genome
Svante Pääbo
Abstract
The discovery of the basis of genetic variation has opened inroads to understanding our history as a species. It has revealed the remarkable genetic similarity we share with other individuals as well as with our closest primate relatives. To understand what make us unique, both as individuals and as a species, we need to consider the genome as a mosaic of discrete segments, each with its own unique history and relatedness to different contemporary and ancestral individuals.