Table of contents
Volume 421 Number 6920 pp195-297
Opinion
Climate come-uppance delayed p195
A proposal to control greenhouse gases may have been dead on arrival in the US Senate — but its time will surely come.
doi:10.1038/421195a
More heat, less light on Lomborg p195
A Danish committee has picked an appropriate target and misfired.
doi:10.1038/421195b
News
US officials urge biologists to vet publications for bioterror risk p197
Erika Check
doi:10.1038/421197a
Gravity experiment sparks spat between physicists p198
Geoff Brumfiel
doi:10.1038/421198a
Safety doubts force rethink of embattled comet mission p198
Declan Butler
doi:10.1038/421198b
Report backs Smithsonian research p198
Erika Check
doi:10.1038/421198c
Prospect of human cloning poses dilemma for journals p199
Helen Pearson
doi:10.1038/421199a
German researchers set to receive Israeli stem-cell shipment p199
Haim Watzman
doi:10.1038/421199b
Paris university blasted over Israel motion p200
Declan Butler
doi:10.1038/421200a
Pesticide firms ask to use human data to assess safety p200
Tony Reichhardt
doi:10.1038/421200b
Ethics panel attacks environment book p201
Alison Abbott
doi:10.1038/421201a
news feature
Burning issues p204
Australia's cities impinge upon an ancient landscape shaped by fire. Carina Dennis talks to the researchers who are striving to protect lives and property, while retaining natural fire regimes that nurture the country's biodiversity.
Carina Dennis
doi:10.1038/421204a
Optical atomic clocks: The times, they are a-changin' p207
More accurate timepieces could lead to better global positioning systems, insights into fundamental physics and a redefinition of the second. David Adam rates the runners in the race to build tomorrow's atomic clocks.
David Adam
doi:10.1038/421207a
Correspondence
Journals: redundant publications are bad news p209
Publishing the same work twice is unethical and casts doubt on the integrity of research.
Stefania M. Mojon-Azzi, Xiaoyi Jiang, Ulrich Wagner and Daniel S. Mojon
doi:10.1038/421209a
Journals: how to decide what's worth publishing p209
Tom Jefferson and Karen Shashok
doi:10.1038/421209b
Journals: impact factors are too highly valued p210
Jamie Davies
doi:10.1038/421210a
Bright students enjoy correcting the textbooks p210
Peter Hughes
doi:10.1038/421210b
Animal research needs organized defence p210
Charles G. Smith
doi:10.1038/421210c
DNA discrepancy p210
Alex May
doi:10.1038/421210d
Book Reviews
Emmet's inch and eagle's mile p211
How scientists sized up all they surveyed.
Lewis Pyenson reviews Measuring America: How an Untamed Wilderness Shaped the United States and Fulfilled the Promise of Democracy by Andro Linklater and The Measure of All Things: The Seven-Year Odyssey and Hidden Error that Transformed the World by Ken Alder
doi:10.1038/421211a
Glue for the mental world p212
Paul Bloom reviews The Big Book of Concepts by Gregory L. Murphy
doi:10.1038/421212a
The ethics of genetics p213
Bonnie Steinbock reviews Genetics and Society: An Introduction by Alison Pilnick and Genetic Politics: From Eugenics to Genome by Anne Kerr and Tom Shakespeare
doi:10.1038/421213a
Gone but not forgotten p213
doi:10.1038/421213b
Science in culture p214
Martin Kemp reviews
doi:10.1038/421214a
concepts
Microbial phylogenomics: Branching out p217
Robert L. Charlebois, Robert G. Beiko and Mark A. Ragan
doi:10.1038/421217a
News and Views
Sugars tied to the spot p219
The interactions of sugars and proteins underlie many biological processes, and cataloguing them is a daunting task. A technique for attaching sugars to microarrays offers a promising, high-throughput solution.
Sabine L. Flitsch and Rein V Ulijn
doi:10.1038/421219a
Functional genomics: RNA sets the standard p220
One way of finding out what genes do is to inactivate them, and to study the effects, in 'model' organisms. That has now been done for many thousands of worm genes in two large-scale analyses.
Thomas Tuschl
doi:10.1038/421220a
Palaeoclimatology: Cooling a continent p221
The effect of greenhouse gases on climate is underscored by modelling work showing that formation of the Antarctic ice sheet, 34 million years ago, occurred largely because of a fall in atmospheric CO2 concentration.
Peter Barrett
doi:10.1038/421221a
Immunology: Mobilizing the army p223
When our bodies are injured or infected, inflammatory cells migrate to the damaged area to carry out rescue and repair work. Interactions between three types of protein may form the basis of a highway to guide these cells.
Steven D. Shapiro
doi:10.1038/421223a
Quantum cryptography: Code-breakers confounded p224
Coherent-state quantum cryptography holds the promise of efficient, secure communication. An experimental demonstration shows that a secure key to the code can be exchanged, even if there is a large transmission loss.
Mark Hillery
doi:10.1038/421224a
100 and 50 years ago p225
doi:10.1038/421225a
Evolutionary biology: Splitting in space p225
Disjunct distributions of closely related species are not necessarily the outcome of passive fragmentation of populations. Instead, they can be the consequence of speciation within a population.
Diethard Tautz
doi:10.1038/421225b
Developmental biology: Germ-cell attraction p226
Cells must often travel long distances to carry out their assigned tasks in the body. New work reveals how the precursors of eggs and sperm are guided during their epic journey to the gonads.
Prabhat S. Kunwar and Ruth Lehmann
doi:10.1038/421226a
news and views in brief p228
doi:10.1038/421228a
Brief Communications
Vulcanology: Interaction between Kilauea and Mauna Loa p229
Last year witnessed an unexpected communication between this pair of volcanoes.
Asta Miklius and Peter Cervelli
doi:10.1038/421229a
First paragraph | Full Text | PDF (195K)
Cell biology (Communication arising): Tubulin acetylation and cell motility p230
Alexander Palazzo, Brian Ackerman and Gregg G. Gundersen
doi:10.1038/421230a
First paragraph | Full Text | PDF (90K)
correction p230
doi:10.1038/421230b
addendum p230
doi:10.1038/421230c
Article
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi p231
Ravi S. Kamath, Andrew G. Fraser, Yan Dong, Gino Poulin, Richard Durbin, Monica Gotta, Alexander Kanapin, Nathalie Le Bot, Sergio Moreno, Marc Sohrmann, David P. Welchman, Peder Zipperlen and Julie Ahringer
doi:10.1038/nature01278
Abstract | Full Text | PDF (393K) | Supplementary information
See also: News and Views by Tuschl
Letters to Nature
Quantum key distribution using gaussian-modulated coherent states p238
Frédéric Grosshans, Gilles Van Assche, Jérôme Wenger, Rosa Brouri, Nicolas J. Cerf and Philippe Grangier
doi:10.1038/nature01289
First paragraph | Full Text | PDF (780K) | Supplementary information
See also: News and Views by Hillery
Single-nanowire electrically driven lasers p241
Xiangfeng Duan, Yu Huang, Ritesh Agarwal and Charles M. Lieber
doi:10.1038/nature01353
First paragraph | Full Text | PDF (413K) | Supplementary information
Rapid Cenozoic glaciation of Antarctica induced by declining atmospheric CO2 p245
Robert M. DeConto and David Pollard
doi:10.1038/nature01290
First paragraph | Full Text | PDF (769K) | Supplementary information
See also: News and Views by Barrett
Evolution of the Archaean crust by delamination and shallow subduction p249
Stephen F. Foley, Stephan Buhre and Dorrit E. Jacob
doi:10.1038/nature01319
First paragraph | Full Text | PDF (306K)
Discovery of abundant hydrothermal venting on the ultraslow-spreading Gakkel ridge in the Arctic Ocean p252
H. N. Edmonds, P. J. Michael, E. T. Baker, D. P. Connelly, J. E. Snow, C. H. Langmuir, H. J. B. Dick, R. Mühe, C. R. German and D. W. Graham
doi:10.1038/nature01351
First paragraph | Full Text | PDF (784K) | Supplementary information
Increased CO2 uncouples growth from isoprene emission in an agriforest ecosystem p256
Todd N. Rosenstiel, Mark J. Potosnak, Kevin L. Griffin, Ray Fall and Russell K. Monson
doi:10.1038/nature01312
First paragraph | Full Text | PDF (276K)
Speciation along environmental gradients p259
Michael Doebeli and Ulf Dieckmann
doi:10.1038/nature01274
First paragraph | Full Text | PDF (517K)
See also: News and Views by Tautz
Loss and recovery of wings in stick insects p264
Michael F. Whiting, Sven Bradler and Taylor Maxwell
doi:10.1038/nature01313
First paragraph | Full Text | PDF (538K) | Supplementary information
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes p268
Kaveh Ashrafi, Francesca Y. Chang, Jennifer L. Watts, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer and Gary Ruvkun
doi:10.1038/nature01279
First paragraph | Full Text | PDF (303K) | Supplementary information
See also: News and Views by Tuschl
Coupling of agonist binding to channel gating in the GABAA receptor p272
Thomas L. Kash, Andrew Jenkins, Jill C. Kelley, James R. Trudell and Neil L. Harrison
doi:10.1038/nature01280
First paragraph | Full Text | PDF (294K) | Supplementary information
Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock p275
J. K. Dale, M. Maroto, M.-L. Dequeant, P. Malapert, M. McGrew and O. Pourquie
doi:10.1038/nature01244
First paragraph | Full Text | PDF (350K)
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor p279
Holger Knaut, Christian Werz, Robert Geisler, The Tübingen 2000 Screen Consortium and Christiane Nüsslein-Volhard
doi:10.1038/nature01338
First paragraph | Full Text | PDF (344K) | Supplementary information
SAP is required for generating long-term humoral immunity p282
Shane Crotty, Ellen N. Kersh, Jennifer Cannons, Pamela L. Schwartzberg and Rafi Ahmed
doi:10.1038/nature01318
First paragraph | Full Text | PDF (735K)
Responses of ferns to red light are mediated by an unconventional photoreceptor p287
Hiroko Kawai, Takeshi Kanegae, Steen Christensen, Tomohiro Kiyosue, Yoshikatsu Sato, Takato Imaizumi, Akeo Kadota and Masamitsu Wada
doi:10.1038/nature01310
First paragraph | Full Text | PDF (366K) | Supplementary information
Direct activation of RNA polymerase III transcription by c-Myc p290
Natividad Gomez-Roman, Carla Grandori, Robert N. Eisenman and Robert J. White
doi:10.1038/nature01327
First paragraph | Full Text | PDF (602K)
erratum: An ultra-sparse code underlies the generation of neural sequences in a songbird p294
Richard H. R. Hahnloser, Alexay A. Kozhevnikov and Michale S. Fee
doi:10.1038/nature01221
erratum: The role of parasites in sympatric and allopatric host diversification p294
Angus Buckling and Paul B. Rainey
doi:10.1038/nature01349
Naturejobs
ProspectsChemistry's clouded view p295
Paul Smaglik
doi:10.1038/nj6920-295a
SPECIAL REPORT
Mobility in Europe p296
Will industry play a bigger role in Europe's aims to promote mobility among postdocs? Susanne Hinck and Quirin Schiermeier investigate.
Susanne Hinck
doi:10.1038/nj6920-296a
