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2002 in context

Nature 420, 732 (19 December 2002) | doi:10.1038/420732a

Small RNAs: The genome's guiding hand?

Carina Dennis

They can be thought of as biology's 'dark matter': tiny RNAs that don't encode any protein. But 2002 has seen an avalanche of discoveries about their roles in influencing gene activity — lending some credence to the radical idea that small RNAs hover 'above' the genome, providing a matrix of regulatory control.