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Alliance for Cellular Signaling Supplement
Nature 420, 708-710 (12 December 2002) | doi:10.1038/nature01305
overview Unravelling the signal-transduction network in B lymphocytes
Gilberto R. Sambrano1, Grischa Chandy2, Sangdun Choi3, Dianne Decamp4, Robert Hsueh4, Keng-Mean Lin4, Dennis Mock5, Nancy O'Rourke2, Tamara Roach6, Hongjun Shu4, Bob Sinkovits5, Mary Verghese2 & Henry Bourne1
Abstract
The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large.
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