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HIV

Conformational camouflage

A study of the thermodynamics of antibody binding to a crucial HIV protein has shed light on why the virus so effectively evades the antibody arm of the immune response. Changes in the protein's conformation are the key.

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Figure 1: Escaping the immune system.

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Correspondence to Theodore Jardetzky.

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Jardetzky, T. Conformational camouflage. Nature 420, 623–624 (2002). https://doi.org/10.1038/420623a

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